000 01643cam a2200325 a 4500
003 EG-GiCUC
005 20250223031737.0
008 170620s2016 ua do f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.12.10.M.Sc.2016.Ay.U
100 0 _aAya Elsayed Elsayed Khedr
245 1 0 _aUses of nitriles and carbonyl compounds in the synthesis of biologically active heterocyclic compounds /
_cAya Elsayed Elsayed Khedr ; Supervised Raafat Milad Mohareb
246 1 5 _aاستخدامات مركبات النيتريل و الكاربونيل لتحضير المركبات غير متجانسة الحلقة ذات النشاط البيولوجى
260 _aCairo :
_bAya Elsayed Elsayed Khedr ,
_c2016
300 _a139 P. :
_bcharts , photographs ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
520 _aIn this work the reaction of ethylacetoacetate (1) with Ü-naphthylamine (2) gave the N-(Naphthalen-1-yl)-3-oxobutanamid (3). The latter products underwent a series of heterocyclization reactions to yield pyridine, pyran, thiophene and pyrazole derivatives. The antitumor evaluations of the newly synthesized products against three cancer cell lines were measured
530 _aIssued also as CD
653 4 _a1,3-dicarbonyl compounds
653 4 _aHeterocycles
653 4 _aSynthesis
700 0 _aRaafat Milad Mohareb ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c61359
_d61359