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008 170702s2016 ua o f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.09.04.Ph.D.2016.Em.C
100 0 _aEman Ahmed Abdelmonem Mohamed Allam
245 1 0 _aChanges in rat parotid and submandibular glands after streptozotocin induced diabetes :
_bAn ultrastructural and histochemical study /
_cEman Ahmed Abdelmonem Mohamed Allam ; Supervised Aly Mohamed Sharawy , Heba Ahmed Farag
246 1 5 _aالتغيرات التى تطرأ على الغدد النكفية و التحت فكية لفئران التجارب المصابة بالسكر نتيجة الحقن بمادة الستربتوزوتوسين :
_bدراسة بواسطة المجهر الالكترونى و نسجية كيميائية
260 _aCairo :
_bEman Ahmed Abdelmonem Mohamed Allam ,
_c2016
300 _a204 P. :
_bphotographs ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology
520 _aNinety male albino rats were used in this study, 12 were used as control groups and the remaining rats were used as experimental groups, diabetes was induced in the experimental groups by streptozotocin. The submandibular and parotid glands were removed and were investigated by several ways as: Haematoxylin and eosin stain. Conventional histochemical staining. Alcian blue (Ph 2.5) for acid mucopolysaccharides. Periodic acid schiff for neutral mucopolysaccharides.Histochemical examination by lectin. Electron microscopy: diabetes mellitus is accompanied with degeneration of acini in the form of fatty changes which increase with increased duration of diabetes, these fatty changes appeared by the electron microscope as lipid droplets within the secretory granules, and within the lysosomes. Degeneration of the serous acini was more severe than the mucous acini. Thick walled and obliterated blood vessels were clearly noticed and were explained by precipitation of neutral mucopolysaccharides as they appered darkly stained by periodic acid schiff in addition to precipitation of galactose as they also appeared darkly stained by lectin. The neuropathy accompanying diabetes is due to delamination of myeline sheath of myelinated nerve fibers, sequestration and hyalinization of the axons as were shown with the electron microscope
530 _aIssued also as CD
653 4 _aOral Pathology
653 4 _aStreptozotocin induced diabetes
653 4 _aSubmandibular glands
700 0 _aAly Mohamed Sharawy ,
_eSupervisor
700 0 _aHeba Ahmed Farag ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c61407
_d61407