000 02500cam a2200349 a 4500
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008 170916s2016 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.18.Ph.D.2016.Ze.C
100 0 _aZeinab Abdelatif Mohamed Sabra
245 1 0 _aCorrelation of endothelial function with oxidative dna damage in obesity and metabolic syndrome /
_cZeinab Abdelatif Mohamed Sabra ; Supervised Rokia Abdelaziz Mohamed , Sahar Abdelaty Sharaf , Mary Wadie Fawzy
246 1 5 _aالعلاقة بين وظيفة الغشاء المبطن للأوعية الدموية و التلف التأكسدى للحمض النووى فى مرض السمنة و متلازمة التمثيل الغذائى
260 _aCairo :
_bZeinab Abdelatif Mohamed Sabra ,
_c2016
300 _a171 P. :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
520 _aBackground: Obesity is a condition where a person has accumulated so much body fat that it might have a negative effect on their health. Metabolic syndrome is a term for a group of conditions, including high blood pressure, high blood sugar and high cholesterol levels, that when combined increase an individual's risk of developing coronary heart disease, stroke and diabetes. Endothelial dysfunction is a well established response to cardiovascular risk factors and precedes the development of atherosclerosis. Oxidative stress (OS) is involved in pathological processes such as obesity, diabetes, cardiovascular disease, and atherogenic processes. Objectives: Assessment of 8-oxodG (oxidative stress biomarker) in obesity and metabolic syndrome and study its relationship to atherosclerosis in obese patients with and without metabolic syndrome. Methods: 52 obese with and without metabolic syndrome will be assessed to levels of 8-oxodG, CIMT and ABI and the results will be compared to 31 healthy controls
530 _aIssued also as CD
653 4 _aEndothelial dysfunction
653 4 _aObesity and Metabolic syndrome
653 4 _aOxidative stress
700 0 _aMary Wadie Fawzy ,
_eSupervisor
700 0 _aRokia Abdelaziz Mohamed ,
_eSupervisor
700 0 _aSahar Abdelaty Sharaf ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c62310
_d62310