000 03078cam a2200349 a 4500
003 EG-GiCUC
005 20250223031810.0
008 170919s2016 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.07.07.M.Sc.2016.Ah.U
100 0 _aAhmed Mahmoud Abdelghany Emara
245 1 4 _aThe use of probiotic bacteria and prebiotic to produce functional dairy products /
_cAhmed Mahmoud Abdelghany Emara ; Supervised Ebtisam Ebrahim Ghita , Mohamed Ahmed Abdelkhalek Azzam , Narges Hassan Mohamed Elsayed
246 1 5 _aاستخدام بكتريا المدعمات الحيوية و المحفزات فى إنتاج أغذية وظيفية لبنية
260 _aCairo :
_bAhmed Mahmoud Abdelghany Emara ,
_c2016
300 _a117 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Agriculture - Department of Dairy
520 _aThe aim of this study was to select the strains with high toleration to simulate human gastrointestinal tract conditions (in vitro), survive in presence of six antibiotics, able to cholesterol assimilation (in vitro) and have the highest antimicrobial activity, among ten of bifidobacteria and leuconostoc strains, in addition to, investigate the promotion and benefit of three food substances as prebiotics for the selected strains, which used in combination as synbiotics. The cholesterol lowering properties of these synbiotics were evaluated (in vivo). Obtained results showed that 5 strains: B. adolescentis a-1, B.longum BB-536, B. longum b-1, Leuconostoc mesenteroides subsp. mesenteroides B-512f and B.bifidum Bb 12 were the most resistant to simulated gastric digestion (pH 3, pH 3+0.3% pepsin, 3% bile salts and 0.5% phenol) and showed high levels of resistance to 6 common antibiotics at the in vitro test compared to the other strains. So these strains were selected for further analyses in vitro to test their growth on prebiotic oligosaccharides, in vitro conditions. 3 strains: B. adolescentis a-1, Leuconostoc mesenteroides subsp. mesenteroides B-512f and B.bifidum Bb 12 were selected with the suitable prebiotics to form synbiotics with high ability to reduce of the lipids and cholesterol of blood serum in rats, in vivo. Also, the results showed that Bifidobacterium bifidum Bb 12 with 1% Inulin and Leuconostoc mesenteroides subsp. mesenteroides B-512f with 1% FOS were more effective for reducing serum TC, LDL-C and TG levels, as well as the atherosclerotic index, in rats fed high-cholesterol diets, and the improving the functions of liver and kidneys of these rats
530 _aIssued also as CD
653 4 _aBifidobacteria
653 4 _aLeuconostoc
653 4 _aProbiotics
700 0 _aEbtisam Ebrahim Ghita ,
_eSupervisor
700 0 _aMohamed Ahmed Abdelkhalek Azzam ,
_eSupervisor
700 0 _aNarges Hassan Mohamed Elsayed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c62430
_d62430