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008 171223s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.07.09.Ph.D.2017.Ho.E
100 0 _aHossam Mahmoud Ibrahem Abotaleb
245 1 0 _aEvaluation of pomegranate (punica granatum l.) freeze dried juice and peel powder extracts as antidiabetic and antihyperlipidemic agents in rats /
_cHossam Mahmoud Ibrahem Abotaleb ; Supervised Mona Mohamed Abdelmagied , Nadia Abdelrahman Salama , Mahmoud Abdallah Mouhamed Saleh
246 1 5 _aتقييم عصير الرمان المجفد و مستخلصات قشور الرمان المجففة كمخفضات للسكر و الدهون في فئران التجارب
260 _aCairo :
_bHossam Mahmoud Ibrahem Abotaleb ,
_c2017
300 _a131 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Agriculture - Department of Food ScienceTechnology
520 _aPunica granatum L., commonly known as pomegranate and belonging to the family of Punicaceae, is a unique plant. Two varieties of pomegranate including Manfaloty and Wonderful were used in this study. The juice powders (JP) subjected to freeze-drying and peel powder extracts (PPE) of the two varieties were used as hypoglycemic and hypocholesterolemic agents by using albino rats. The juice powder was used in two different concentrations (1 and 1.5 g/kg/day/ rat), meanwhile the peel powder extract was used in only one concentration (0.2 g/kg/day/rat). Results show the effect of JP and PPE on the glucose level of diabetic rats. The superior effect was with G6 rats administrated with 0.2 g MPE/kg/day/rat (Manfaloty peel extract) followed by G9 0.2 g WPE/kg/day/rat (Wonderful peel extract). On the other hand results show the effect of JP and PPE on the level of total cholesterol, LDL, HDL and triglycerides in rats serum as hypocholesterolemic agents. These results show that G5 (HFD +1%cholesterol+ 0.2g MPE/kg /day/ rat) recorded the best results of all the aforementioned experiments, this could be attributed to the phenolic content in peel powder extract of pomegranate. The histopathological examination of Pancreas show that G6 and G9 of diabetic rats administrated orally with 0.2g MPE or 0.2 g WPE/kg b.w/day had improvement in pancreatic damage and there was marked improvement in islets structure, meanwhile, Histological examination of liver show that G5 and G8 of rats fed HFD +1% cholesterol administrated orally 0.2g MPE or 0.2 g WPE/kg b.w/day had improvement in histological structure and showed an almost normal structure with a regular arrangement of hepatic cell cords and exhibited a reduction in fat accumulation. Chicken patties prepared with 1.5g MJP or 1.5g WJP recorded the highest values for quality characteristic and microbiology examination as well as sensory evaluations
530 _aIssued also as CD
653 4 _aJuice powder
653 4 _aPeel
653 4 _aPomegranate
700 0 _aMahmoud Abdallah Mouhamed Saleh ,
_eSupervisor
700 0 _aMona Mohamed Abdelmagied ,
_eSupervisor
700 0 _aNadia Abdelrahman Salama ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c64168
_d64168