000 03484cam a2200349 a 4500
003 EG-GiCUC
005 20250223031911.0
008 180108s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.09.10.M.Sc.2017.Di.A
100 0 _aDina Gamal Abdelall
245 1 0 _aAntibacterial activity of chitosan-based coating electrophoretically deposited on titanium implant :
_bAn in vitro study /
_cDina Gamal Abdelall ; Supervised Azza Mohammed Abdelzaher Hashem , Heba Abdelhamed Shalaby , Rasha mohamed abdelraouf
246 1 5 _aالنشاط المضاد للبكتريا لغرسات التيتانيوم المطليه كهربياً المعتمدة على الكيتوزان :
_bدراسة معملية
260 _aCairo :
_bDina Gamal Abdelall ,
_c2017
300 _a123 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Dental Materials
520 _a1.Implant-associated infections are one of the most serious complications in orthopedic surgery and a major cause of implant failure. Establishing antibacterial surface at titanium implant surface is crucial for osseointegration and long-term success of the implants. Therefore, various surface modifications have been developed to Ti-6Al-4V implants in an attempt to prevent bacterial colonization and prevent the implant loss. So, coating the titanium dental implant with chitosan biologically active molecule has been applied with using electrophoresis technology. 2.In this study, electrophoretic deposition of chitosan and hybrid chitosan/HA composite structures coatings was employed to prepare antibacterial titanium dental implant surfaces. Two hundred and twenty Ti-6Al-4V discs were divided equally into five groups to receive different surface coating. Group 1; Native (untreated) implant discs "control group". Group 2; discs coated with chitosan biologically active molecule.Group3; discs coated with calcium phosphate intermediate layer act as carrier. Group 4; for composite structure, discs coated with chitosan/calcium phosphate with the lower current density (I=1.5mA/cm2). Group 5; discs coated with chitosan/calcium phosphate with higher current density (I=2mA/cm2). The different coated Ti-alloy discs were characterized by XRD, FTIR, ESEM and SEM. Coat weight of different deposited surfaces were assessed by sensitive balance. The quantities of chitosan deposited on Ti-alloy were monitored by chitosan indicative FTIR bands. The release rate of chitosan was monitored by quantitative analysis of the chitosan characteristics functional groups and the amount of weight loss at different time intervals; 48, 96,192 and 384 hrs. Antibacterial activity of activated chitosan and composite hybrid chitosan coating was assessed against two bacterial strains; S. aureus and E. coli by using Colony forming units' plate counting method (CFU)
530 _aIssued also as CD
653 4 _aAntibacterial activity of chitosan-based
653 4 _aElectrophoretically deposited
653 4 _aTitanium implan
700 0 _aAzza Mohammed Abdelzaher Hashem ,
_eSupervisor
700 0 _aHeba Abdelhamed Shalaby ,
_eSupervisor
700 0 _aRasha mohamed abdelraouf ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c64465
_d64465