000 03008cam a2200349 a 4500
003 EG-GiCUC
005 20250223032004.0
008 180509s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.24.M.Sc.2017.Sa.A
100 0 _aSally Farouk Fathy Elgendy
245 1 0 _aAssessment of retinal ganglion cell complex thickness in diabetic patients before and after intravitreal injection ofanti-vegf agents (ranibizumab) by spectral domain O.C.T :
_cSally Farouk Fathy Elgendy ; Supervised Ali Mohamed Taha , Khaled Gamal Abualenen , Noha Mahmoud Khalil
246 1 5 _aتقييم سمك طبقة الخلايا العقديه بالشبكية في مرضي السكر قبل وبعد حقن عقار الليوسنتس داخل العين باستخدام جهاز التصوير الطبقي بالترابط الضوئي ذو المجال الطيفي
260 _aCairo :
_bSally Farouk Fathy Elgendy ,
_c2017
300 _a103 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Ophthalmology
520 _aPurpose:To evaluate retinal ganglion cell complex thickness before and after Ranibizumab intravitreal injection in patients of diabetic macular edema using spectral domain optical coherence tomography (SD-OCT) scans.Methods : prospective interventional case series ,Thirty- three eyes of 27 patientswith diabetic macular edema were imaged by spectral domain optical coherence tomography (SD-OCT) before receiving Ranibizumabintravitreal injection,4 weeks and 2 months after injection . thickness changes in retinal ganglion cell complex after 3 months follow up period were quantitatively analyzed and correlated. Results:There is a statistical significant decrease in Average Retinal ganglion cell complex thicknessas well as the superior and inferior ganglion cell thickness ( P value <0.001, 0.000 and 0.000 ) respectively. The correlation between ganglion cell complex thickness values and duration of diabetes mellitus shows no statistical significant relation .Conclusion : Intra-vitreal Ranibizumab injection cause significant reduction in the Average, superior,inferior thickness of retinal ganglion cell layer in diabetic patients along 3 months follow up period ,with negative correlation between duration of diabetes and ganglion cell complex thickness parameters.Further studies with larger sample,longer follow-up and greater number of injections ,are warranted
530 _aIssued also as CD
653 4 _aDiabetic Macular Edema
653 4 _aIntravitreal Ranibizumab Injection
653 4 _aRetina
700 0 _aAli Mohamed Taha ,
_eSupervisor
700 0 _aKhaled Gamal Abualenen ,
_eSupervisor
700 0 _aNoha Mahmoud Khalil ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c66160
_d66160