| 000 | 03238cam a2200349 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 005 | 20250223032046.0 | ||
| 008 | 180920s2018 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.22.Ph.D.2018.Ma.R | ||
| 100 | 0 | _aMai Hussein Abdelkarim | |
| 245 | 1 | 4 |
_aThe role of bone marrow biopsy and FDG-PET/CT in identifying bone marrow infiltration in newly diagnosed cases of high grade non-Hodgkin B-cell lymphoma and Hodgkin lymphoma / _cMai Hussein Abdelkarim ; Supervised Ahmed Abdelsamie Kandeel , Jehan Ahmed Younis , Wael Abdel Gawad |
| 246 | 1 | 5 | _aدور خزعة النخاع و المسح الذري البوز تروني المدمج بالأشعة المقطعية في تحديد إصابة نخاع العظام في حالات سرطان الغدد الليمفاوية قبل العلاج |
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_aCairo : _bMai Hussein Abdelkarim , _c2018 |
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_a158 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Nuclear Medicine | ||
| 520 | _aAim of work:To compare between FDG PET/CT and routine iliac bone marrow biopsy (BMB) in assessment of bone marrow infiltration in Hodgkin lymphoma (HL) and aggressive non-Hodgkin lymphoma (NHL) lymphoma patient at presentation. Patients and Methods: This prospectivestudy was conducted on 138 patients (50 HL, 88 NHL). The study included 70 male and 68 female with median age of 43 years (range 20-70 years). All patients had pre therapy FDG PET/CT and BMB. Results Concordance between PET/CT and BMB was observed in 104 (75.4%) of 138 patients. Both tests were negative in 86 patients and both were reported positive in 18 patients. Among the 88 NHL, bone marrow infiltration (BMI) was detected by PET/CT in 26 (29.5%) and by BMB in 22 (25%), the concordance was detected in 64 (72.7%) patients, both tests were negative in 52 and positive in 12 patients (p 0.003). In 50 HL, BMI was detected by PET/CT in 14 (28%) and by BMB in 8 (16%), the concordance between PET/CT and BMB was detected in 40 (80%) patients, both tests were negative in 34 patients and positive in 6 patients (p 0.001). The overall results revealed a border line significant higher sensitivity for FDG PET/CT (73.9%) compared to BMB (62.5%) (p 0.046). FDG PET-CT provides upstaging in 8.6% of the enclosed patients. In HL group, PET/CT showed significantly higher sensitivity compared to BMB being 87.5% versus 50% (p 0.02).While For NHL group, comparable results of sensitivity were seen in PET/CT and BMB being 66.7%, versus 68.8% (p<0.1). Conclusion: FDG PET/CT seemed to be a promising alternative tool to BMB in assessment of BMI at initial assessment of HL & NHL lymphoma | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aFDG PET/CT | |
| 653 | 4 | _aHodgkin lymphoma | |
| 653 | 4 | _aNon-Hodgkin lymphoma | |
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_aAhmed Abdelsamie Kandeel , _eSupervisor |
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| 700 | 0 |
_aJehan Ahmed Younis , _eSupervisor |
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| 700 | 0 |
_aWael Abdel Gawad , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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_aShimaa _eCataloger |
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_2ddc _cTH |
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_c67568 _d67568 |
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