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008 180924s2018 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.10.13.Ph.D.2018.Wi.E
100 0 _aWissam Abdullah Yousif Alhayani
245 1 0 _aEfficiency of adipose derived mesenchymal stem cells on regeneration of facial nerve neurotmesis in Rabbits /
_cWissam Abdullah Yousif Alhayani ; Supervuised Faisal A. Torad , Ahmed I. Abdelglil , Laila A. Rashed
246 1 5 _aتاثير الخلايا الجذعية المستخلصة من الخلايا الدهنية على تجديد العصب الوجهي المتهتك في الأرانب
260 _aCairo :
_bWissam Abdullah Yousif Alhayani ,
_c2018
300 _a160 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Surgery - Anesthesiology and Radiology
520 _aThe aim of this study was to evaluate the efficiency of polyglycolic acid mesh and the polyglycolic acid mesh seeded with adipose derived stem cells as a conduit and compared it with control group for regeneration of facial nerve defect in rabbits. A 24 healthy adult rabbits were randomly divided into three equal groups (n=8). In the group A, a 0.5 cm of left buccal branch facial nerve was transected andcoaptated using polyglycolic acid mesh conduit only. In group B, a 0.5 cm of left buccal branch facial nerve was transected andcoaptated using polyglycolic acid mesh seeded with adipose derived stem cells (ADSCs). In group C (control), a 0.5 cm of left buccal branch facial nerve was transected and left without anastomosis.Clinical,histomorphometric, gross pathological, histopathological and electron microscopical evaluations were done. The result showed that, the polyglycolic acid mesh and the polyglycolic acid mesh seeded with adipose derived stem cells enhanced nerve healing across nerve defect and polyglycolic acid mesh seeded with adipose derived stem cells provides better and significant improvement in facial nerve regeneration in rabbits than empty polyglycolic acid mesh conduit and no regeneration was occurred in control group
530 _aIssued also as CD
653 4 _aAdipose-derived stem cells
653 4 _aFacial nerve defect
653 4 _aPolyglycolic acid mesh
700 0 _aAhmed I. Abdelglil ,
_eSupervisor
700 0 _aFaisal A. Torad ,
_eSupervisor
700 0 _aLaila A. Rashed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c67636
_d67636