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008 180926s2018 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2018.Eh.S
100 0 _aEhab Mohamed Mohamed Alahwal
245 1 0 _aSoluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as inflammatory biomarker in cystic fibrosis /
_cEhab Mohamed Mohamed Alahwal ; Supervised Noussa Ragab Mohamed , Hanan Ali Madani , Hanan Mohsen Osman
246 1 5 _aمستقبل الإثارة السائل الممثل على الخلايا النخاعية (ترم1) كمعامل حيوى للالتهاب فى مرض التليف الكيسى
260 _aCairo :
_bEhab Mohamed Mohamed Alahwal ,
_c2018
300 _a152 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aCystic fibrosis (CF) is an autosomal recessive disease with significant associated morbidity and mortality. A cross sectional study included 60 patients diagnosed as cystic fibrosis (CF) age and sex matched with 30 healthy children as control group. Thirty-seven (61.7%) patients were males and 23 (38.3%) were females. Serum samples of patients collected from cystic fibrosis clinic in specialized Children Hospital, Cairo University, to detect serum levels of sTREM-1. HRCT chest was done and brody score was used to evaluate the degree of lung affection in CF cases. There was significant elevation of (sTREM-1) in the plasma of CF patients than healthy control group (P value = 0.001) but no significant difference in level of (sTREM-1) between stable and exacerbated CF patients (P value =1). In this study there was no correlation between sTREM-1 levels and HRCT scoring (P=0.903) and no correlation between sTREM-1 and CRP (P=0.445). This study demonstrated significant trends for progression of severity of lung disease with increasing patient age (p < 0.05) regarding overall CT brody score
530 _aIssued also as CD
653 4 _aCystic fibrosis
653 4 _aHigh resolution computerized tomografy
653 4 _aSweat chloride
700 0 _aHanan Ali Madani ,
_eSupervisor
700 0 _aHanan Mohsen Osman ,
_eSupervisor
700 0 _aNoussa Ragab Mohamed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c67658
_d67658