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008 180927s2017 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.24.M.Sc.2017.Mo.C
100 0 _aMona Kassem Kassem Mostafa
245 1 0 _aCorrelation between corneal hysteresis, corneal thickness and IOP in patient of rheumatoid arthritis and their relation to the disease activity /
_cMona Kassem Kassem Mostafa ; Supervised Rasha Mounir Eltanamly , Ashraf Ahmed Nossair , Yomna Amr
246 1 5 _aدراسة الارتباط بين تماسك القرنية و سمكها العين فى مرضى التهاب المفاصل الروماتويدى و علاقتهم بنشاط المرض
260 _aCairo :
_bMona Kassem Kassem Mostafa ,
_c2017
300 _a81 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Ophthalmology
520 _aPurpose: To evaluate the corneal biomechanical properties by using Ocular Response analyzer ORA to measure corneal hysteresis, corneal resistance factor and IOPcc and correlate them with central corneal thickness in Rheumatoid arthritis patients and correlate it with the disease activity. Patients and methods: The study is a cross sectional study in which rheumatoid arthritis patients scheduled for full ophthalmic examination, measuring intraocular pressure measurement (IOP) using the ocular response analyzer (ORA), the goldman applanation tonometer (GAT) and central corneal thickness CCT by using optical coherence tomography (OCT) in the same day after assessment of the disease activity by rheumatologist using CDAI score activity then statistical analysis was done for all the results. Results: Forty rheumatoid arthritis patients were enrolled in the study, 4 males and 36 females the mean age of patients involved is 42.8 (± ), ranging between 30 and 70 years. Obtainability of ORA was significantly higher than GAT in both groups (active and inactive). Strong correlations existed between GAT and ORA measurements. Strong negative correlation between CDAI and CCT in the active group. Significant positive correlation between CRF and CCT in the inactive group. No statistically significant difference between ORA parameters, OCT pachymetery or IOP GAT between two groups. Conclusion: ORA has proven to be superior to GAT in the ability to obtain reliable IOP measurements in RA. Central corneal thickness was negatively correlated with CDAI activity score. Corneal biomechanical properties could have been affected and persisted in RA in active or remission disease phase
530 _aIssued also as CD
653 4 _aIntraocular pressure
653 4 _aOcular response analyzer
653 4 _aRA
700 0 _aAshraf Ahmed Nossair ,
_eSupervisor
700 0 _aRasha Mounir Eltanamly ,
_eSupervisor
700 0 _aYomna Amr ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c67701
_d67701