000			03322cam a2200349 a 4500
003			EG-GiCUC
005			20250223032055.0
008			181008s2018 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.04.M.Sc.2018.Mo.R
100	0		_aMohammed Helmy Aly Ahmed
245	1	0	_aRelationship between myeloperoxidase level in systemic & coronary arterial circulation in patients with non st segment elevation - acute coronary syndrome / _cMohammed Helmy Aly Ahmed ; Supervised Yasser Kamel Gaber Baghdady , Noha Hassanin Mohammed , Assem Abdelaziz Hashad
246	1	5	_aST العلاقة ب{u٠٦أأ}ن مستوى الما{u٠٦أأ}لوب{u٠٦أأ}روكس{u٠٦أأ}داز في الدورة الدمو{u٠٦أأ}ة الرئ{u٠٦أأ}س{u٠٦أأ}ة والدورة الدمو{u٠٦أأ}ة بالشرا{u٠٦أأ}{u٠٦أأ}ن التاج{u٠٦أأ}ة في مرضى قصور الشرا{u٠٦أأ}{u٠٦أأ}ن التاج{u٠٦أأ}ة الحاد الغ{u٠٦أأ}ر مصاحب بارتفاع فقرة
260			_aCairo : _bMohammed Helmy Aly Ahmed , _c2018
300			_a108 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology
520			_aBackground: Inflammation andoxidative stress have played important roles in all stages of the evolution of atherosclerotic plaque, from the early development of endothelial dysfunction.(1) Myeloperoxidase participates in proatherogenic biological activities related to the evolution of cardiovascular disease, including initiation, propagation and acute complications of atherosclerotic process.(2) In this study we identified the relationship between myeloperoxidase (MPO) and the severity of coronary artery disease (CAD). Methods: we measured the level of MPO in the peripheral venous circulation and the coronary arteries in patients with CAD and compared them to the levels of MPO in a control group who don{u2019}t have CAD. The severity of CAD was quantitated using the CASS (vessel) score and the Gensini score. Results: This study was performed on 86 patients (divided into case and control groups) recruited over 3 months duration in the cardiovascular department of Cairo university hospital. We found a strong correlation between serum MPO and severity of coronary artery disease as measured using the Vessel (CASS) score (p=0.05) and the Gensini score. (p=0.002). We also have found that the peripheral venous serum level of MPO correlates with the intracoronary arterial serum levels of MPO and the differences were not statistically significant. Conclusions: There is a Correlation between the serum MPO and the severity of coronary artery disease. The peripheral venous serum level of MPO reflects the intracoronary arterial serum levels of MPO
530			_aIssued also as CD
653		4	_aAcute coronary syndrome
653		4	_aGensisi score
653		4	_aMyeloperoxidase
700	0		_aAssem Abdelaziz Hashad , _eSupervisor
700	0		_aNoha Hassanin Mohammed , _eSupervisor
700	0		_aYasser Kamel Gaber Baghdady , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c67836 _d67836