000			03295cam a2200337 a 4500
003			EG-GiCUC
005			20250223032107.0
008			181029s2018 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.10.M.Sc.2018.Ri.C
100	0		_aRiham Mohye Eldeen Mohamed Morsy
245	1	2	_aA comparative study of TCA 35% and phenol 88% peels as monotherapy versus combination therapy with N-acetyl-L-cysteine in patchy alopecia areata : _bA trichoscopic evaluation / _cRiham Mohye Eldeen Mohamed Morsy ; Supervised Doaa Mohamed Ali Mahgoub , Sarah Ibrahim Ismail
246	1	5	_aتقييم التقشير بثلاثي حمض الخليك ثلاثي الكلور {u٠٦ئ٣}٥٪ والفينول ٨٨٪ مقابل اقتران كل منهما على حدة بدواء إن أسيتيل سيستيين لعلاج الثعلبة البقعي: _bباستخدام التريكوسكوب
260			_aCairo : _bRiham Mohye Eldeen Mohamed Morsy , _c2018
300			_a146 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology
520			_aBackground: Alopecia areata (AA) is a tissue-specific autoimmune disorder wherein anagen hair follicles sustain a T-cell-mediated inflammatory assault. It commonly presents with circumscribed patches of non-scarring hair loss. It implies a significant psychosocial burden. A myriad of therapeutic modalities are available for the treatment of AA, but none has yet proven uniformly effective. Chemical peeling can potentially be used in the treatment of AA; primarily acting via therapeutic wounding with subsequent release of growth factors and cytokines. Aim of work: To evaluate the efficacy, safety, and tolerability of TCA 35% peel in comparison to phenol peel 88% in AA treatment, to determine whether oral N-acetyl-L-cysteine (NALC) has an additive value to chemical peels in subjects with AA, and to assess the impact of these interventions on patients{u2019} quality of life. Methodology: A total of 20 patients with multifocal patchy AA of the scalp ({u2265}2 patches) were enrolled,wherein a total of 40 patches were subjected to chemical peeling byTCA 35% and phenol 88%; each applied to a distinct patch in the same individual, respectively, in tandem, on 3-weekly basis for 3 consecutive months. Within the studied group, subjects were further randomized to two equal Groups; either Group A (Chemoexfoliation monotherapy) or Group B (Chemoexfoliation combined with oral NALC).Comparative assessment was carried out utilizing trichoscopic scaled scores of dystrophic and terminal hairs, respectively, SALT score, DLQI score as well as the global patients{u2019} satisfaction scaled score. Adverse effects were monitored clinically, trichoscopically, and via direct questioning
530			_aIssued also as CD
653		4	_aChemical peeling
653		4	_aMultifocal patchy alopecia areata
653		4	_aTCA 35%
700	0		_aDoaa Mohamed Ali Mahgoub , _eSupervisor
700	0		_aSarah Ibrahim Ismail , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c68215 _d68215