000			03442cam a2200349 a 4500
003			EG-GiCUC
005			20250223032120.0
008			181124s2018 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2018.Do.T
100	0		_aDoaa Mostafa Mohammed Refaay Elshemy
245	1	0	_aTissue doppler versus conventional echocardiography and serum cardiac troponin i in assessment of myocardial performance in perinatally asphyxiated full term neonates / _cDoaa Mostafa Mohammed Refaay Elshemy ; Supervised Mohamed Saad Elbaz , Walaa Alsharany Abuelhamed , Alaa Eldin Adel Sobeih
246	1	5	_aتقييم أداء عضلة القلب بواسطة الدوبلر النسيجى بالمقارنة بالموجات الصوتية الاعتيادية على القلب و التروبونين فى الأطفال الذين يعانون من الاختناق الوليدى
260			_aCairo : _bDoaa Mostafa Mohammed Refaay Elshemy , _c2018
300			_a162 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aIntroduction: Myocardial functions are affected by the stress conditions such as shock and hypoxia. Signs of myocardial dysfunction depend on the severity of the injury. Hypoxia in the asphyxiated newborns often causes myocardial dysfunction. Objectives: The current study is designed to assess myocardial performance of full-term infants with perinatal asphyxia using tissue Doppler imaging (TDI) and to correlate it with serum cardiac troponin I( cTnI) concentrations. Material and methods: Twenty asphyxiated full-term newborn were consecutively enrolled in this study and another cross-matched twenty normal newborns as control group. All patients were subjected to measurement Serum cTnI concentrations that were measured between 12 and 24 hours of life. Conventional two-dimensional Doppler echocardiography and TDI were done during the {uFB01}rst 72 hours of life. Results: Cases with HIE had significant elevation of cTnI (p= 0.007), and serum troponin was significantly elevated among non-survivors newborns (p=0.008). Also lower pH and higher cTnI were significantly associated with higher risk of mortality among neonates with HIE (p=0.036 and p=0.038) respectively. There was significant difference between cases and controls as regards LV-DD in both pulsed wave and TDI (p<0.001); while the RV-DD showed no statistically difference between both groups .In our study, analysis of cutoff values, sensitivity, specificity, and area under ROC curves for dif»ferent markers of myocardial dysfunction revealed that serum cTnI, LV-E'/A', IVS-E'/A' and RV-E'/A' showed the highest diagnostic/prognostic values in predicting mortality in asphyxiated infants compared to other parameters (sensitivity 88.9%, 88.9%, 88.9%, 77.8% and specificity 72.7%, 45.5%, 63.6% and 54.5%respectively)
530			_aIssued also as CD
653		4	_aEchocardiography
653		4	_aPerinatal asphyxia
653		4	_aTissue Doppler imaging
700	0		_aAlaa Eldin Adel Sobeih , _eSupervisor
700	0		_aMohamed Saad Elbaz , _eSupervisor
700	0		_aWalaa Alsharany Abuelhamed , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c68665 _d68665