000 02997cam a2200349 a 4500
003 EG-GiCUC
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008 181124s2018 ua ho f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2018.Do.C
100 0 _aDoaa Ahmed Mahmoud Nasr
245 1 0 _aChildhood acute ITP, epidemiology, management and long-term outcome :
_bA ten-year retrospective study /
_cDoaa Ahmed Mahmoud Nasr ; Supervised Nadia Abdelrahman Zaghlool , Magy Samir Abdelwahab , Rasha Abdelraouf Abdelaziz
246 1 5 _aمرض قلة الصفيحات الدمويه المناعى الحاد بالأطفال: معدل إنتشا ره: طرق علاجه ونتائج ذلك على المدى الطويل
260 _aCairo :
_bDoaa Ahmed Mahmoud Nasr,
_c2018
300 _a96 P. :
_bfacsimiles , Photographs ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aAim of the work: In the current study, we aimed to illustrate features, epidemiology of acute immune thrombocytopenia (ITP) andestimate the prevalence and long-term outcome of acute ITP in our community. Also we aimed to compare the effect of different treatment regimens on the outcome and to estimate the percentage of chronicity and its predictive factors. Moreover, we aimed to establish a protocol of management and follow up guided by the results of our study.Subjects and methods: This is a 10 year observational retrospective study that included medical record reviewof 526 patients. All cases data collected included; name , sex, date of birth ,age at presentation, platelet count and bleeding symptoms , treatment received and response , complication(s) of disease ,and therapy (if they arise) including splenectomy. Patients' data in the first year of presentation were recorded including response to therapy and final outcome.Results: Among 526 patients there was 281 male and 245 female with (M: F) ratio 1.14:1, with a mean age 5 ± 3.2 years. Patients presented with skin bleeds in the form of purpura or ecchymosis in 349 patients (66.3%), mucous membrane bleeds as epistaxis or gum bleeding in 30 patients (5.7%) or both skin and mucous membrane bleeding in 137 patients (26%). The mean presenting platelet count was 18±17.6 x109/L. medical treatment was administered to 82.3% of patients with acute ITP but 17.7% did not receive any treatment. Seventy-three (13.8% of all patients) of those who received no treatment showed spontaneous remission
530 _aIssued also as CD
653 4 _aITP
653 4 _aPurpura
653 4 _aResponse
700 0 _aMagy Samir Abdelwahab ,
_eSupervisor
700 0 _aNadia Abdelrahman Zaghlool ,
_eSupervisor
700 0 _aRasha Abdelraouf Abdelaziz ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c68672
_d68672