| 000 | 02621cam a2200349 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 005 | 20250223032145.0 | ||
| 008 | 190109s2018 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.08.07.M.Sc.2018.Mo.P | ||
| 100 | 0 | _aMohamed Sayed Abdelhafeez Hassan | |
| 245 | 1 | 0 |
_aPhytochemical assessment of certain biologically selected plants as antidiabetic drugs / _cMohamed Sayed Abdelhafeez Hassan ; Supervised Soad Hanna Tadros , Omayma Dawoud Elgindi , Dalia Adel M. Al Mahdy |
| 246 | 1 | 5 | _aتقييم فيتوكيميائى لبعض النباتات المختارة ذات الفاعلية البيولوجية كمضاد لمرض السكر |
| 260 |
_aCairo : _bMohamed Sayed Abdelhafeez Hassan , _c2018 |
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| 300 |
_a197 P. : _bcharts , facsimiles; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy | ||
| 520 | _aBackground : The prevalence of Diabetes mellitus in middle-income countries is considered a major health problem that needs to be addressed appropriately. A comparative evaluation of antidiabetic activities of three selected plants cultivated in Egypt namely; mango leaves, rosemary leaves and barley grains was performed to establish their potentials. Method: The plant extracts were prepared using ethanol (70%) and fractionated with petroleum ether, methylene chloride, ethyl acetate and n-butanol. The antihyperglycemic activity of the extracts, fractions and isolated Ý-glucan were tested in-vitro using Ü-glucosidase and Ü-amylase inhibitory assays. Meanwhile the in-vivo anti-hyperglycemia and antioxidant studies were carried out on the total extracts and isolated Ý-glucan in alloxan induced diabetic rats. Quality control parameters were established for the selected samples including proximate analysis, determination of macro- and micronutrients, amino acids profile and vitamins content. Phytochemical investigation of the biologically active fractions was established followed by HPLC standardization finally LC-MS profiling of the secondary metabolites of the selected drugs | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aAntidiabetic drugs | |
| 653 | 4 | _aMango leaves | |
| 653 | 4 | _aRosemary leaves and barley grains | |
| 700 | 0 |
_aDalia Adel Mohamed Almahdy , _eSupervisor |
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| 700 | 0 |
_aOmayma Dawoud Elgindi , _eSupervisor |
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| 700 | 0 |
_aSoad Hanna Tadros , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aEnas _eCataloger |
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| 905 |
_aNazla _eRevisor |
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| 942 |
_2ddc _cTH |
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| 999 |
_c69463 _d69463 |
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