000 02679cam a2200349 a 4500
003 EG-GiCUC
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008 190216s2018 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.22.Ph.D.2018.Ma.C
100 0 _aMahmoud Shaban Ahmed Abdelaleem
245 1 0 _aClinical significance of diffuse hepatic uptake on post-ablative radio-iodine scan in differentiated thyroid cancer /
_cMahmoud Shaban Ahmed Abdelaleem ; Supervised Sherif Elrefaei , Alaa Abdelhalim Marzok , Rehab Ahmed Abdelmaguid
246 1 5 _aالقيمة الإكلينيكية للالتقاط الكلى للكبد لليود المشع في المسح الذرى بعد الجرعة العلاجية في مرضى السرطان المتباين للغدة الدرقية
260 _aCairo :
_bMahmoud Shaban Ahmed Abdelaleem ,
_c2018
300 _a87 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Nuclear Medicine
520 _aBackground: The aim of this study was to investigate whether diffuse hepatic and thyroid bed uptake of 131I on post-ablative whole body iodine scans (PAWBIS) of patients with differentiated thyroid cancer (DTC) have any relevance for clinical outcome and parameters. Patients and Methods: We prospectively investigated 195 patients with DTC, who were treated at Kasr-Alainy Hospital, Cairo University from 2015 to 2017. Grades of hepatic and thyroid bed uptake on 131I whole body scan were classified from 0 to 3 by visual assessment. Recurrence-free survival was evaluated with the Kaplan-Meier method and Cox regression analysis. Results: Male patients (p< 0.004) above 45 years (p < 0.005) having tumors larger than 1 cm (p = 0.005), multiple tumor foci (p < 0.02), and a higher TNM stage (p < 0.003) with positive history of metastatic cervical LNs (p < 0.05) were associated with bad outcomes. Female patients, unifocal tumors and high grades of liver uptake were identified as independent good prognostic factors with (p values 0.048, 0.042, 0.009) respectively. Intense thyroid bed uptake and faint hepatic activity were related to poor prognosis
530 _aIssued also as CD
653 4 _aDiffuse hepatic
653 4 _aRadio-iodine scan
653 4 _aThyroid cancer
700 0 _aAlaa Abdelhalim Marzok ,
_eSupervisor
700 0 _aRehab Ahmed Abdelmaguid,
_eSupervisor
700 0 _aSherif Elrefaei ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c70228
_d70228