000			02886cam a2200349 a 4500
003			EG-GiCUC
005			20250223032222.0
008			190307s2018 ua h f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.24.M.Sc.2018.Sa.E
100	0		_aSara Hamed Mohamed Bargees
245	1	0	_aEvaluation of retinal nerve fiber layer and macular thickness in patients with systemic lupus erythematosus / _cSara Hamed Mohamed Bargees ; Supervised Soheir Mohamed Esmat , Mohamad Amr Salah Eldin , Mohamed Mahmoud Khafagy
246	1	5	_aتقييم الالياف العصبية وسمك ماقولة شبكية العين فى مرضى الذئبة الحمراء
260			_aCairo : _bSara Hamed Mohamed Bargees , _c2018
300			_a67 P. : _bfacsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Ophotographs
520			_aIntroduction: The aim of the study was to evaluate changes that occur in the retinal layers in systemic lupus erythematosus (SLE) patients using SD-OCT, confirming the value of OCT as an easy, rapid and non invasive imaging technique that can be used in early detection and follow up of retinal involvement in SLE disease. It was performed at the department of Ophthalmology, Kasr Al Ainy hospital, Cairo University in 14 months{u2019} duration. Method: The study was a cross sectional observational, case-control, non-randomized study. It included 77 eyes of 77 individuals divided into two groups; group A (SLE patients), group B (control). All patients had a full ophthalmological examination and OCT assessment of central foveal thickness (CFT), retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses and all data were correlated to each other. Results: The average CFT in group A was 226.45±26.9, and in group B it was 248.2æ±19.04, with statistically significantly difference (p<0.001). The average RNFL thickness in group A was 108.81 æ±12.41, and in group B it was 113.42æ±4.98, also with a statistically significant difference (p=0.041). As for the average GCC thickness in group A it was 107.67 æ±10.76, while in group B it was 113.52 æ±7.76, which was significantly different (p=0.008). Conclusion: OCT parameters (CFT, RNFL and GCC) are the key parameters that can be used for early detection and follow up of SLE effect on the retina and the optic nerve head
530			_aIssued also as CD
653		4	_aFiber layer
653		4	_aMacular thickness
653		4	_aRetinal nerve
700	0		_aMohamad Amr Salah Eldin , _eSupervisor
700	0		_aMohamed Mahmoud Khafagy , _eSupervisor
700	0		_aSoheir Mohamed Esmat , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c70697 _d70697