000 02742cam a2200349 a 4500
003 EG-GiCUC
005 20250223032229.0
008 190319s2018 ua dho f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.24.03.Ph.D.2018.Ta.R
100 0 _aTamer Mohsen Ahmed Elnahas
245 1 0 _aRandomized prospective study on the use of laser assisted hatching for transfer of frozen / thawed embryos in human intracytoplasmic sperm injection /
_cTamer Mohsen Ahmed Elnahas ; Supervised Mohamed Amr Hussein Elnory , Mohamed Ahmed Aboulghar , Osama Mahmoud Azmy
246 1 5 _aدراسة عشوائية محتملة لتأثير الليزر كمحفز لفقس الاجنة المجمدة فى حالات الحقن المجهرى
260 _aCairo :
_bTamer Mohsen Ahmed Elnahas ,
_c2018
300 _a91 P. :
_bcharts , facsimiles , photographs ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Application in Medical and Biological
520 _aBackground: Cryopreservation of human embryos has become an essential part of assisted reproduction, however it might be associated with zonal hardening, which could reduce implantation rates and clinical pregnancy rates. Assisted hatching has been used to induce microdissection of the zona pellucida. Many techniques have been used. Such as mechanical, chemical, piezo and laser techniques. Objective: To determine if laser assisted hatching improves both the implantation and clinical pregnancy rates in women using transferred frozen/thawed embryos. Patients and methods: 160 women. Scheduled for transfer of cryopreserved embryos, were randomized in two equal groups using sealed envelopes; a laser assisted hatching group (test group), and a control group, each included 80 women. On the day of embryo transfer. Diode laser was used in LAH group to induce zonal microdissection. The quality and safety of the embryos are assisted morphologically after hatching and also by measuring malondialdehyde before and after application of laser to determine if laser might be a source of oxidative stress, which affects embryos quality, implantation rates and pregnancy rates
530 _aIssued also as CD
653 4 _aCryopreservation
653 4 _aLaser assisted hatching for transfer of frozen
653 4 _aPregnancy rates
700 0 _aMohamed Ahmed Aboulghar ,
_eSupervisor
700 0 _aMohamed Amr Hussein Elnory ,
_eSupervisor
700 0 _aOsama Mahmoud Azmy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c70928
_d70928