000 02488cam a2200349 a 4500
003 EG-GiCUC
005 20250223032247.0
008 190418s2018 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.10.10.M.Sc.2018.Sh.P
100 0 _aShimaa Ahmed Abdelbaki
245 1 0 _aPreparation of horse polyvalent antiserum against rhodococcus equi and evaluation of its therapeutic and prophylactic efficacy /
_cShimaa Ahmed Abdelbaki ; Supervised Rafik Tawfik Mohamed Soliman , Mohamed Youssef Salah Mattok , George Abdelmalak Habib
246 1 5 _aتحضير مصل خيول متعدد ضد بكتريا الرودوكوكس اكواى و تقييم قدرته العلاجية و الوقائية
260 _aCairo :
_bShimaa Ahmed Abdelbaki ,
_c2018
300 _a127 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology
520 _aRhodococcus equi, a Gram-positive facultative intracellular pathogen, is among the most widely recognized causes of pneumonia in foals. Several antimicrobial drugs are effective against R. equi in vitro; however, many of these agents are ineffective in vivo because of the capability of R. equi to survive and replicates in macrophages. The present study aimed to prepare R. equi-specific hyperimmune horse antiserum and to evaluate its therapeutic and prophylactic efficacy against R. equi infection. Four horses were immunized with a locally prepared formalin inactivated R. equi vaccine adjuvanted with mineral oil. Each of these horses was immunized with 3 doses of the prepared vaccine (3ml/ dose) at 2 weeks intervals. One week after the last vaccination dose, serum from immunized horses was collected by plasmapheresis. The measured titer of R. equi specific antibodies reached to 104 ELISA units/ml after 2 weeks from the primary immunization and up to 105 ELISA units/ml one week after the third immunization dose
530 _aIssued also as CD
653 4 _aELISA
653 4 _aPolyvalent antibodies
653 4 _aRhodococcus equi
700 0 _aGeorge Abdelmalak Habib ,
_eSupervisor
700 0 _aMohamed Youssef Salah Mattok ,
_eSupervisor
700 0 _aRafik Tawfik Mohamed Soliman ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAsmaa
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c71541
_d71541