| 000 | 02697cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032255.0 | ||
| 008 | 190505s2018 ua dho f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.24.03.Ph.D.2018.Sh.E | ||
| 100 | 0 | _aShahenda Ahmad Ramez | |
| 245 | 1 | 0 |
_aEvaluation of the topical delivery of methotrexate combined with fractional erbium : _bYAG laser in the treatment of plaque psoriasis / _cShahenda Ahmad Ramez ; Supervised Mona Mohamed Soliman , Maha Fadel Mohamed Ali , Faisal Nour Eldeen Mohamed |
| 246 | 1 | 5 | _aتقيين التوصيل الموضعى للميثوتريكسات مع الإربيوم ياج ليزر المجزأ فى علاج الصدفية اللويحية |
| 260 |
_aCairo : _bShahenda Ahmad Ramez , _c2018 |
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| 300 |
_a88 P. : _bcharts , facsimiles , photoghraphs ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - National Institute of Enhanced Laser Sciences - Department of Laser Applications in Medical and Biological | ||
| 520 | _aPsoriasis is a commonly encountered chronic dermatological disease, presenting with inflammatory symptoms in patients. Systemic treatment of psoriasis is associated with several adverse effects; therefore the development of a customized topical treatment modality for psoriasis would be an interesting alternative to systemic delivery. The therapeutic modality explored in this study was the comparative treatment of psoriatic patients using nanoparticulated methotrexate in the form of jojoba oil based microemulsion with or without fractional erbium YAG laser. Assessment parameters included follow up photography for up to 8 weeks of treatment, estimation of the psoriasis severity score of the treated lesions which is the score of thickness, erythema, scales (TES score), and histopathological skin evaluation. Results revealed that the prepared methotrexate microemulsion was clinically beneficial and safe in treatment of psoriasis vulgaris. The concomitant use of the fractional laser provided improvement in the psoriatic plaques within shorter time duration (3 weeks compared to 8 weeks of treatment), presenting an alternative topical treatment modality for psoriasis vulgaris | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aMethotrexate | |
| 653 | 4 | _aNanocarrier | |
| 653 | 4 | _aPsoriasis | |
| 700 | 0 |
_aFaisal Nour Eldeen Mohamed , _eSupervisor |
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| 700 | 0 |
_aMaha Fadel Mohamed Ali , _eSupervisor |
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| 700 | 0 |
_aMona Mohamed Soliman , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c71801 _d71801 |
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