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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.02.Ph.D.2018.Ab.P
100 0 _aAbdelsattar Abdelsattar Ibrahim
245 1 0 _aPossible therapeutic effect of platelet- rich plasma on induced knee osteoarthritis in adult male albino rat :
_bHistological and immunohistochemical study /
_cAbdelsattar Abdelsattar Ibrahim ; Supervised Ibrahim Labib Abdallah , Medhat Mohammed Morsi , Laila Rashid Ahmed
246 1 5 _aالتأثير العلاجي المحتمل للبلازما الغنية بالصفائح الدموية في الإلتهاب العظمي المفصلي التنكسي المستحدث في ركبة ذكر الفأرالأبيض البالغ :
_bدراسة هستولوجية وهستوكيميائية مناعية
260 _aCairo :
_bAbdelsattar Abdelsattar Ibrahim ,
_c2018
300 _a119 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anatomy
520 _aPurpose: Osteoarthritis (OA) is a degenerative joint disease. OA is characterized by chronic joint pain and dysfunction which represent a major cause of disability. This work was done to assess the efficacy of autologous PRP injection on induced osteoarthritis in adult male albino rats using light microscope and immunohistochemical study. Methods: One hundred adult male albino rats were divided into five groups, the articular cartilages of the femoral condyles were prepared for histological and immunohistochemical examination. Results: Osteoarthritic group showed loss of zonation, disoriented cells, irregularly eroded surface, decreased articular thickness, many ghost cells, clefts, moderately to weakly stained matrix, and decreased immunohistochemical reaction. Treated group showed marked improvement of all these changes. Untreated group showed no improvement and some times more deterioration. Conclusion: It could be concluded that the results support the application of autologous platelets- rich plasma as an effective method in the treatment of osteoarthritis being confirmed by the improvement of the histological and immunohistochemical reactions of the articular cartilage
530 _aIssued also as CD
653 4 _aOsteoarthritis
653 4 _aPRP
653 4 _aRat
700 0 _aIbrahim Labib Abdallah ,
_eSupervisor
700 0 _aLaila Rashid Ahmed ,
_eSupervisor
700 0 _aMedhat Mohammed Morsi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c71917
_d71917