| 000 | 02594cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032300.0 | ||
| 008 | 190513s2018 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.27.Ph.D.2018.Yo.I | ||
| 100 | 0 | _aYousra Ossama Kamal Eldin | |
| 245 | 1 | 0 |
_aImmunohistochemical study of ezrin expression in colorectal carcinoma / _cYousra Ossama Kamal Eldin ; Supervised Ali Ahmed Foad Elhindawi , Essam Ezzat Ayad , Mona Salah Eldin Abdelmagid |
| 246 | 1 | 5 | _aدراسة مناعية هستوكيميائية للتعبير عن الإزرين فى سرطان القولون |
| 260 |
_aCairo : _bYousra Ossama Kamal Eldin , _c2018 |
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| 300 |
_a162 P. : _bcharts , facimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pathology | ||
| 520 | _aBackground: Colorectal cancer is the third most common type of cancer and the fourth leading cause of cancer-related deaths worldwide. Ezrin is involved in maintaining cell structure and cell motility. Expression levels of the ezrin gene correlate with numerous human malignancies. Aim of this work: to determine the significance of ezrin in the development and progression of colorectal carcinoma to provide the evidence for clinical prognosis and suitable adjuvant therapy. Material & Methods: Ezrin expression was evaluated in fifty one cases of colorectal carcinoma by using two methods; objective and quantitative method to determine the statistical relation between ezrin objective analysis score and clinicopathological parameters and to do a comparative study between both methods of analysis. Results: Ezrin was expressed in 92.2% of cases, and it showed a statistical significant relation with tumor grade.There was no statistical relationship between ezrin expression and different clinicopathological findings. A statistically significant relation was found between ezrin objective analysis score and ezrin quantitative analysis score (P-value <0.05). A strong positive Pearson correlation exists between both methods of analysis (R=0.868) | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aColorectal cancer | |
| 653 | 4 | _aColorectal carcinoma | |
| 653 | 4 | _aEzrin | |
| 700 | 0 |
_aAli Ahmed Foad Elhindawi , _eSupervior |
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| 700 | 0 |
_aEssam Ezzat Ayad , _eSupervior |
|
| 700 | 0 |
_aMona Salah Eldin Abdelmagid , _eSupervior |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c71949 _d71949 |
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