000 02310cam a2200337 a 4500
003 EG-GiCUC
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008 190713s2018 ua ho f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.28.Ph.D.2018.Su.A
100 0 _aSusan Mohamed Amer
245 1 0 _aAutoantibody pattern in Egyptian juvenile dermatomyositis patients /
_cSusan Mohamed Amer ; Supervised Samia Salah Eldin Mahmoud , Azza Abdelkadr Elhamshary , Samar Mohamed Sabri
246 1 5 _aنمط الأضداد الذاتية في مرضى التهاب الجلد والعضلات المصريين
260 _aCairo :
_bSusan Mohamed Amer ,
_c2018
300 _a200 P. :
_bfacsimiles , ohptpghraphs ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aJuvenile dermatomyositis (JDM), the most common inflammatory myopathy of child hood, is a rare multisystemic autoimmune vasculopathy. This study assesses autoantibody pattern in Egyptian patients with Juvenile dermatomyositis. This study conducted on 11 JDM patients. Serum autoantibody level was measured using extractable nuclear antigens by hybridization. The age of patients ranged from 5.5 to 15 years with a mean of 10.3 years. Sixty four% (64%) of JDM patients were females and thirty six% (36%) were males with a male to female ratio 1:2. The most common presenting manifestations in the study group were musculoskeletal manifestations (100%) dermatological manifestations (100%), and difficulty of swallowing (dysphagia) (9%). EMG was done for all patient and there was myopathic changes in (100%) of patients. Our results for autoantibodies done in this study were negative.Conclusion: Serum autoantibodies done in the study cannot be used as reliable marker for diagnosis or assessing disease activity
530 _aIssued also as CD
653 4 _aAutoantibody
653 4 _aJuvenile dermatomyositis
653 4 _aMyopathy and vasculopathy
700 0 _aAzza Abdelkadr Elhamshary ,
_eSupervisor
700 0 _aSamia Salah Eldin Mahmoud ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c72801
_d72801