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003 EG-GiCUC
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008 190717s2019 ua do f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.07.M.Sc.2019.Ba.P
100 0 _aBassma Mohamed Ali Elkawe
245 1 2 _aA pharmacognostical study of coccoloba peltata schott family polygonaceae /
_cBassma Mohamed Ali Elkawe ; Supervised Abdlrahman Omar Elshabrawy , Mona Goda Zagloul , Riham Salah Eldine Elsayed
246 1 5 _aدراسة عقاق{u٠٦أأ}ر{u٠٦أأ}ة لنبات كوكولوبا بلتاتا شوت من العائلة البطباط{u٠٦أأ}ة
260 _aCairo :
_bBassma Mohamed Ali Elkawe ,
_c2019
300 _a230 P. :
_bcharts , photographs ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy
520 _aCoccoloba peltata Schott is a sprawling, small, evergreen tree mainly native to Brazil. Biological study of the ethanolic extract and the fraction of the leaves involved both in-vitro assessment of the cytotoxic and anti-oxidant activities, and in-vivo anti-diabetic parameters of the leaves. The in-vitro activities were screened using colorimetric MTT and ABTs scavenging assays, respectively and the in-vivo anti-diabetic parameters including hypoglycemic activity, glucose tolerance test and STZ-induced diabetes mellitus. Five known compounds: phytosterols (Ý-sistosterol and Ý-sitosterol-3-O-Ý-glucoside), anthraquinones (1-methyl emodin and emodin) and triterpene (olean-12-en-2Ü,3Ý-diol) have been isolated from the chloroform fraction of the ethanolic extract, identified via physicochemical and spectroscopic analyses. Phytochemical investigation of the ethyl acetate fraction of the leaves of C. peltata resulted in isolation of the gallic acid and myricitrin. The total phenolic content of the leaves was 65.1 æg GAE/g extract and the total flavonoid content was 58.2 æg QE/g extract
530 _aIssued also as CD
653 4 _aBiological screening
653 4 _aBotanical study
653 4 _aCoccoloba peltata Schott
700 0 _aAbdlrahman Omar Elshabrawy ,
_eSupervisor
700 0 _aMona Goda Zagloul ,
_eSupervisor
700 0 _aRiham Salah Eldine Elsayed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAsmaa
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c72924
_d72924