| 000 | 02522cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032332.0 | ||
| 008 | 190720s2018 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.09.Ph.D.2018.Ra.S | ||
| 100 | 0 | _aRamadan Ahmed Ahmed Khalil | |
| 245 | 1 | 0 |
_aSodium valproate versus continous infusion of haloperidol in management of agitated critically ill patients / _cRamadan Ahmed Ahmed Khalil ; Supervised Khaled Hussein Mohamed , Mohamed Omar Abdelsadek , Mohamed Soliman Said |
| 246 | 1 | 5 | _aمقارنة عقار صوديم فالبروات بعقار الهالوبريدول في علاج الهياج العصبي المصاحب لمرضى الحالات الحرجة |
| 260 |
_aCairo : _bRamadan Ahmed Ahmed Khalil , _c2018 |
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| 300 |
_a142 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine | ||
| 520 | _aDepakene is an antiepileptic and mood stabilizer approved for treatment of seizures, manic episodes associated with bipolar disorder, and migraine prophylaxis. Mechanistically, it blocks voltage-dependent sodium and calcium channels, increases Þ- aminobutyric acid (GABA) synthesis, potentiates GABA activity at postsynaptic receptors, blocks GABA degradation, and attenuates the activity of glutamate upon N-methyl-D-Aspartate receptors (Perucca E.2002 & Rosenberg G.2007). Recently, valproate has been administered to critically ill patients to treat agitation and delirium, but there are few published reports to support this practice (Bourgeois JA,et al.2005),( SherY, et al.2015) & (Fitz K, Harding A.2011).Valproate is an emerging treatment for ICU agitation because it allows patients to interact with their caregivers; can be administered outside of the ICU; has both an intravenous (IV) and enteral formulation; has a low drug acquisition cost; and has not been associated with respiratory depression, hemodynamic derangements, or delirium | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aGABA | |
| 653 | 4 | _aHaloperidol | |
| 653 | 4 | _aSodium valproate versus | |
| 700 | 0 |
_aKhaled Hussein Mohamed , _eSupervisor |
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| 700 | 0 |
_aMohamed Omar Abdelsadek , _eSupervisor |
|
| 700 | 0 |
_aMohamed Soliman Said , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c72996 _d72996 |
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