000			03028cam a2200349 a 4500
003			EG-GiCUC
005			20250223032333.0
008			190722s2018 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.18.M.Sc.2018.Fa.E
100	0		_aFatma Mohamed Mokhtar Tolba Fayed
245	1	0	_aEvaluation of serum level of long non-coding rna (uc001ykl.1) in systemic lupus erythematosus and behcet{u2019}s disease and its correlation with disease activity / _cFatma Mohamed Mokhtar Tolba Fayed ; Supervised Ahmed AbdelMoaty Elnaggar , Noha Adly Seddiq , Laila Ahmed Rashed
246	1	5	_a فى الدم للمرضى المصريين المصابين بمرض الذئبة الحمراء ومرض بهجت وعلاقته بنشاط المرض فى كل منهما(uc001ykl.1) غير المرمّز للبروتين RNA تقييم مستوى شرائط الحمض الريبوزى
260			_aCairo : _bFatma Mohamed Mokhtar Tolba Fayed , _c2018
300			_a177 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
520			_aBackground: Long non-codig RNAs are RNA transcripts more than 200 nucleotides in length, which do not encode proteins. Recent studies have reported that differentiation and activation of immune cells, T cells, B cells, macrophages, and natural killer (NK) cells have correlation with long non-coding RNAs, which have also an essential role in autoimmune diseases such as systemic lupus erythematosus and Behcet{u2019}s disease. Objectives: This study aims to assess the expression of long non-coding RNA uc001ykl.1 among SLE patients and BD patients compared to healthy controls and correlation of its level with disease activity in any of both diseases. Methods: Thirty Egyptian patients with SLE (according to ACR revised criteria 1997), thirty Behçet{u2019}s disease Egyptian patients (according to the international study group of Behçet{u2019}s disease 2010) and 30 (age and sex matched) apparently healthy Egyptian controls were enrolled in our study. All our patients were subjected to full history taking and full clinical examination. Disease activity of our SLE patients was determined using the SLEDAI-2k form while BD patients{u2019} activity was assessed using BDCAF. Laboratory investigations in the form of CBC, ESR, CRP, liver function tests and kidney functions were done to all our patients. Uc001ykl.1 was assessed by PCR to all our patients and controls
530			_aIssued also as CD
653		4	_aBehcet's disease
653		4	_along non coding RNA
653		4	_aSystemic lupus erythematosus
700	0		_aAhmed AbdelMoaty Elnaggar , _eSupervisor
700	0		_aLaila Ahmed Rashed , _eSupervisor
700	0		_aNoha Adly Seddiq , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c73031 _d73031