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| 003 | EG-GiCUC | ||
| 005 | 20250223032348.0 | ||
| 008 | 190829s2019 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.02.Ph.D.2019.Al.E | ||
| 100 | 0 | _aAli Ahmed Ali Kotb Mousa | |
| 245 | 1 | 0 |
_aEffect of stem cells and melatonin on amiodarone-treated thyroid gland in adult male albino rat: histological, histomorphometrical and immunohistochemical study / _cAli Ahmed Ali Kotb Mousa ; Supervised Soheir Hanafi Ahmed , Ehab Abdelaziz Ahmed Elshaarawy , Mogeda Mahdy Nasrallah |
| 246 | 1 | 5 | _aتأثير الخلايا الجذعية والميلاتونين علي الغدة الدرقية المعالجة بالأميودارون في ذكر الفار الأبيض البالغ: دراسة هستولوجية وهستومورفولوجية قياسية و هستوكيميائية مناعية |
| 260 |
_aCairo : _bAli Ahmed Ali Kotb Mousa , _c2019 |
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| 300 |
_a129 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anatomy | ||
| 520 | _aIn the present study it was found that amiodarone administration in rats by gastric gavage tube resulted in changes in thyroid gland. These changes were in hormonal levels, histological and immunohistochemical changes. These changes were improved by treating rats with stem cells. Also, adding melatonin to the stem cells culture was found to have further beneficial effect. The present study was carried out to investigate the structural and functional changes in the thyroid gland following the administration of amiodarone, and to assess the possible role of stem cells and melatonin supplement in minimizing these changes in the gland of adult male albino rat as an animal model. On the other hand, malondialdehyde levels in thyroid tissue expressed a highly significant increase in groups III and IV compared to control group, while group V showed increased in only a significant manner than the control. Meanwhile, group IV and V showed statistically significant decrease from Group III. Also, group V decrease was insignificantly different from that of group IV. The PCR results showed highly significant increase of both IL-6 and VEGF in group III compared to the control one. Groups IV and V showed a highly significant decrease compared to group III | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aHistomorphometrical | |
| 653 | 4 | _aMelatonin | |
| 653 | 4 | _aThyroid Gland | |
| 700 | 0 |
_aEhab Abdelaziz Ahmed Elshaarawy , _eSupervisor |
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| 700 | 0 |
_aMogeda Mahdy Nasrallah , _eSupervisor |
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| 700 | 0 |
_aSoheir Hanafi Ahmed , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aAsmaa _eCataloger |
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| 905 |
_aNazla _eRevisor |
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_2ddc _cTH |
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| 999 |
_c73552 _d73552 |
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