000			02109cam a2200349 a 4500
003			EG-GiCUC
005			20250223032353.0
008			190908s2019 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.10.10.Ph.D.2019.Sa.E
100	0		_aSally Magdy Abdelsalam Abdelhamid
245	1	0	_aEffect of various stabilizers on efficacy of live attenuated brucella RB51 vaccine / _cSally Magdy Abdelsalam Abdelhamid ; Supervised Khaled Farouk Elamry , Khaled Abdelkader Abdelazeem , Ahmed Samir Mohamed
246	1	5	_aتاثير المثبتات المختلفة علي كفاءة لقاح البروسيلا اربي51
260			_aCairo : _bSally Magdy Abdelsalam Abdelhamid , _c2019
300			_a94 P. : _bcharts ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology
520			_aBrucellaabortusstrain RB51 is a cattle vaccine that is approved for use in the U.S. for prevention of brucellosis. At the present time,Egypt is considering the use of SRB51 vaccine in their brucellosis control programs. In the current study, the effect of five stabilizing media, on the viability of lyophilized SRB51 over a 52 week period and the characteristics of the immune responses triggered by vaccination with locally prepared RB51 vaccine are determined. 5 groups of mice immunized with the prepared RB51 vaccines and subsequently challenged with high virulent B.abortus544 were protected from reinfection. Post vaccination, the early production of gamma interferon seems to have the prominent role in inducing an immunologically based protection
530			_aIssued also as CD
653		4	_aBrucellaabortus
653		4	_aRB51
653		4	_aVaccines
700	0		_aAhmed Samir Mohamed , _eSupervised
700	0		_aKhaled Abdelkader Abdelazeem , _eSupervised
700	0		_aKhaled Farouk Elamry , _eSupervised
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c73717 _d73717