000 03404cam a2200349 a 4500
003 EG-GiCUC
005 20250223032431.0
008 191105s2019 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.07.M.Sc.2019.Ne.P
100 0 _aNermeen Bahaa Eldine Ali
245 1 2 _aA phytochemical and biological study of kalanchoe beharensis drake (fam. crassulaceae), cultivated in Egypt /
_cNermeen Bahaa Eldine Ali ; Supervised Marawan Marawan Shabana , Essam Abdelhamid Abdelsattar , Sabah Hussein Elgayed
246 1 5 _aدراسة فيتوكيميائية وبيولوجية لنبات كالنشو بيهارنسيس (العائلة المخلديه) المنزرع فى مصر
260 _aCairo :
_bNermeen Bahaa Eldine Ali ,
_c2019
300 _a210 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy
520 _aKalanchoe beharensis Drake is a popular garden succulent evergreen shrub native to Madagascar, but it has been cultivated in Egypt as an ornamental plant. It is commonly known as elephant's ear kalanchoe. It belongs to Genus Kalanchoe, one of the largest Genera of family Crassulaceae. Numerous species of this genus were reported to be used traditionally for the treatment of many health ailments and have been investigated for important biological properties. Reviewing the current literature, little data about K. beharensis were traced concerning its biological activities or phytoconstituents. Consequently, it is a matter of interest to investigate its biological activities and phytochemical composition. For confirmation of the raw material quality and purity as well as differentiation of the plant under study from other Kalanchoe species, criteria for characterization was established via determination of the morphological features, proximate analysis and phytochemical screening. The air-dried powdered leaves were exhaustively extracted by 90% ethanol then the total extract subjected to successive extraction by liquid-liquid fractionation using solvents of increasing polarities; with petroleum ether, chloroform, ethyl acetate and n-butanol saturated with water. All fractions were exposed to repeated chromatographic fractionation that led to the isolation of eight compounds, Four compounds were isolated for the first time from genus Kalanchoe (1-Triacontanol fatty alcohol, Quercetin-3-O-Ý-xylopyrnosyl-(1"'{u2192}2")-O-Ý-glucoside, Myricetin-3-O-Ý-xylopyranosyl-(1"'{u2192}2")-O-Ý-galactoside and Myricetin-3-O-Ý-galactoside); two compounds were previously isolated from genus Kalanchoe, but it is the first report of their isolation from K. beharensis leaves (Ý-Sitosterol and Ý-Sitosterol-3-O-Ý-glucoside) and the other two compounds were previously isolated from K. beharensis leaves (Quercetin and Quercetin-3-O-Ý-galactoside)
530 _aIssued also as CD
653 4 _aAntioxidant
653 4 _aElephant's ear kalanchoe
653 4 _aKalanchoe beharensis Drake
700 0 _aEssam Abdelhamid Abdelsattar ,
_eSupervisor
700 0 _aMarawan Marawan Shabana ,
_eSupervisor
700 0 _aSabah Hussein Elgayed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAsmaa
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c74998
_d74998