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003 EG-GiCUC
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008 191120s2019 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.10.10.Ph.D.2019.Am.T
100 0 _aAmani Elsayed Mahdi Marawan
245 1 0 _aTrials for preparation of vaccine against campylobacter species in chicken /
_cAmani Elsayed Mahdi Marawan ; Supervised Heidy M. Shawky , Ahmed S. Mohamed , Ahmed M. Ammar
246 1 5 _aمحاولات لتحضير لقاح ضد أنواع الكامبيليوباكتر فى الدجاج
260 _aCairo :
_bAmani Elsayed Mahdi Marawan ,
_c2019
300 _a135 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology
520 _aCampylobacter is a worldwide infection, which has been estimated as the most significant economic burden by EFSA and ECDC in 2016. It caused mainly by either Campylobacter jejuni or Campylobacter coli. Campylobacter species are one of the main cause of gastroenteritis for humans in developed and developing countries. The disease is endemic in Egypt and is a major cause of diarrhea in children. Good understanding of epidemiology and surveillance of Campylobacter will help in the elimination and prevention of it among animals and humans. Several intervention strategies have been implemented to reduce the intestinal colonization in chicken and vaccination measures is one of the effective control methods. The main goal of the present study was to develop a vaccine for reducing the intestinal burden of Campylobacter in chickens. To achieve this, 290 samples were collected from broiler flocks and slaughter market from Cairo governorate, Egypt. Vaccination of chickens with a prepared killed whole-cell vaccine was carried out.The Campylobacter specific IgG were measured in collected serum samples using ELISA assay. Also, Campylobacter count in the cecal content and serum antibody which have been measured. The greatest reduction in C.jejuni colonization was determined. Production of Campylobacter specific IgG antibodies as well as a marked decrease in C.jejuni colonization were recorded in chickens. In conclusion, we approved that the vaccination with CWC provides 73.3% protection of chickens from C.jejuni colonization
530 _aIssued also as CD
653 4 _aCampylobacter jejuni
653 4 _aChicken
653 4 _aColonization
700 0 _aAhmed M. Ammar ,
_eSupervisor
700 0 _aAhmed S. Mohamed ,
_eSupervisor
700 0 _aHeidy M. Shawky ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c75341
_d75341