| 000 | 02992cam a2200349 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 005 | 20250223032445.0 | ||
| 008 | 191123s2019 ua dbo f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.12.10.Ph.D.2019.Mo.C | ||
| 100 | 0 | _aMohamed Samy Mansour Abdelwahab | |
| 245 | 1 | 0 |
_aChemical characterization and evaluation of the moringa oleifera and moringa peregrina leaf extracts growing in Egypt as anticancer and antimicrobial agents / _cMohamed Samy Mansour Abdelwahab ; Supervised Ismail Abdelshafy Abdelhamid , Hanaiya A. Elitriby , Magda Fikry Mahmoud Mohamed |
| 246 | 1 | 5 | _aالتوصيف الكيميائى وتقييم مستخلصات اوراق شجرة المورينجا اوليفيرا والمورينجا برجرينا التى تنمو بمصر كمضادات للسرطان والميكروبات |
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_aCairo : _bMohamed Samy Mansour Abdelwahab , _c2019 |
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| 300 |
_a99 P. : _bcharts , maps , photoghraphs ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Organic Chemistry | ||
| 520 | _aMoringa grows in the tropical and subtropical regions of the world. the genus Moringa belonging to family Moringaceae. It is found to possess various medicinal uses including hypoglycemic, analgesic, anti-inflammatory, hypo-lipidemic and antioxidant activities. In this study we investigated the anti-cancer and anti-microbial activity of the moringa oleifera and moringa peregrina leaves extracts which grown locally in Egypt. The anticancer activity tested against hepatocellular carcinoma (HepG2) and breast carcinoma (MCF-7) cancer cell lines. the extracts of leaves showed notable anti-cancer properties. Also, the toxicity was significantly low in both moringa oleifera and moringa peregrina leaves extracts using the normal melanocytes cell line (HFB4). In addition, cell cycle progression, apoptosis and (BAX, BCL2, P53, CASP3 and MMP1) genes expression evaluation were done to evaluate this anticancer effect. Many bioactive phytochemicals compounds with known anti-cancer activity were identified using the GC/MS analyses.This proposes that the anti-cancer properties of moringa oleifera and moringa peregrina leaves extracts could be attributed to these phytochemical compounds existing inside it. Additionally, the anti-microbial activity against gram positive bacteria, gram negative bacteria and Fungi were done. Most of the extracts found to possess high antimicrobial activity | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aExtraction | |
| 653 | 4 | _aMoringa oleifera | |
| 653 | 4 | _aMoringa peregrine | |
| 700 | 0 |
_aHanaiya A. Elitriby , _eSupervisor |
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| 700 | 0 |
_aIsmail Abdelshafy Abdelhamid , _eSupervisor |
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| 700 | 0 |
_aMagda Fikry Mahmoud Mohamed , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c75412 _d75412 |
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