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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.33.M.Sc.2019.Ah.R
100 0 _aAhmed Bahaa Eldin Abbas
245 1 2 _aA randomized study comparing moxifloxacin, omeprazole, nitazoxanide, and doxycycline versus classic triple therapy for the eradication of helicobacter pylori /
_cAhmed Bahaa Eldin Abbas ; Supervised Maissa Elsaid Elraziky , Mohammad Elsayed Soliman , Walied Khalid Alhossary
246 1 5 _aدراسة عشوائية تقارن بين الموكسيفلوكساسين والاوميبرازول والنيتازوكسانيد و الدوكسيسيكلين مقابل العلاج الثلاىى الكلاسيكى في علاج البكتيريا الحلزونيه
260 _aCairo :
_bAhmed Bahaa Eldin Abbas ,
_c2019
300 _a75 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine
520 _aIntroduction:Helicobacter pylori infection is a global concern with rising antimicrobial resistance and declining cure rates which has led to an increased demand for a more efficacious, yet tolerable, therapy. Aim: To evaluate the efficacy and safety of the two regimens (Amoxicillin, clarithromycin and omeprazole for 14 days vs moxifloxacin, doxycycline, nitazoxanide and omeprazole for 14 days) as a first-line treatment for Helicobacter pylori (H. pylori) infection. Patients &Methods: From September 2018 to April 2019, 90 patients with confirmed H. pylori infection were randomized into two groups.The First group (triple group)(n = 44) received amoxicillin 1000 mg, clarithromycin500 mg and Omeprazole 40 mg twice a day for 14 days, the Second group (MOND group) (n = 46) received Moxifloxacin 400 mg, Doxycycline 100 mg once daily, Nitazoxanide 500 mg and Omeprazole 40 mg twice a day for 14 days. Successful eradication of H. pylori infection was defined as a negative Stool antigen test 6 weeks after the end of treatment. Patient compliance was defined as 2good3 if drug intake was at least 90%.Follow up of patient'sadherenceto treatment, adverse event rates and dyspepsia improvement was done 6 weeks after theend of treatment
530 _aIssued also as CD
653 4 _aHelicobacter pylori
653 4 _aMoxifloxacin
653 4 _aTreatment
700 0 _aMaissa Elsaid Elraziky ,
_eSupervisor
700 0 _aMohammad Elsayed Soliman ,
_eSupervisor
700 0 _aWalied Khalid Alhossary ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c75503
_d75503