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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.10.09.M.Sc.2019.No.E
100 0 _aNoha Mohamed Elsayed Darwish
245 1 0 _aEvaluation of oxidative stress biomarkers for diagnosis of selected gastrointestinal diseases of dogs /
_cNoha Mohamed Elsayed Darwish ; Supervised Adel A. Kubesy , Noha Y. Salem
246 1 5 _aتقييم مستوى دلائل الإجهاد التأكسدى لتشخيص الأمراض المعدمعوية المختارة فى الكلاب
260 _aCairo :
_bNoha Mohamed Elsayed Darwish ,
_c2019
300 _a97 P. :
_bphotographs ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Internal Medicine and Infectious Diseases
520 _aGastrointestinal disorders are one of the most common affections encountered in veterinary canine practice and reasons for seeking veterinary assistance in small animal practice. They have multiple etiologies to occur for example food indiscretions, allergies, drug interactions, viral, bacterial, and parasitic infection. The most signified signs are vomiting and diarrhea. This current study targeted to estimate alteration on hematology and oxidative stress biomarkers in selected gastrointestinal diseases. This study enrolled 64 dogs, divided into 22 apparently healthy dog served as control and 42 diseased dogs (14 suffered from canine parvovirus enteritis; 10 dogs with gastroenteritis caused by parasitic infection; 10 Suffered from gastritis and 8 Suffered from enteritis). Blood samples were collected from each animal for clinical hematology, oxidant biomarkers MDA, H2O2 and antioxidant biomarkers SOD, GPX, Catalase, TAC, Zn, Cu, iron. Cortisol level, Cl and k were also estimated in serum. Dogs with parvovirus infection showed increase in MDA, H2O2, SOD, GPX, and decrease of catalase, Zn, Cu and Fe. Increased SOD, MDA, and cortisol, with decrease in GPx, catalase, Cu, Zn and Fe were recorded in both gastritis group and enteritis group. However, H2O2 level decreased in gastritis and increased in enteritis group. In dogs with gastroenteritis caused by parasitic infection, drop in hemoglobin, PCV, catalase and GPx along with rise in SOD and cortisol were recorded. In conclusion, alteration in oxidant stress biomarkers is associated with presented gastrointestinal disorders
530 _aIssued also as CD
653 4 _aCanine
653 4 _aMalondialdehyde
653 4 _aOxidative stress biomarker
700 0 _aAdel Abdelbaset Mohamed Kubesy ,
_eSupervisor
700 0 _aNoha Yousef Mohamed Salem ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c75699
_d75699