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| 008 | 191209s2019 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.08.06.M.Sc.2019.Ah.M | ||
| 100 | 0 | _aAhmed Abdelmonaem Ammar | |
| 245 | 1 | 0 |
_aMicrobiological studies on the production of serratia-peptidase as an anti-inflammatory from serratia species / _cAhmed Abdelmonaem Ammar ; Supervised Magdy Ali Amin , Reham Samir , Wael Mohamed Abuelwafa |
| 246 | 1 | 5 | _aدراسات ميكروبيولوجية على إنتاج إنزيم السيريشياببتيديز كمضاد للالتهاب من بكتيريا السيريشيا |
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_aCairo : _bAhmed Abdelmonaem Ammar , _c2019 |
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| 300 |
_a133 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology | ||
| 520 | _aProteases constitute one of the most important groups of industrial enzymes, accounting for more than 65% of the industrial enzyme market. Microbial proteases produced from microbes belonging to bacteria, fungi, yeast and actinomycete, account for approximately 40% of the total worldwide sales of enzymes. Serratiopeptidase is a proteolytic enzyme that has been used as anti-inflammatory agent in sinusitis, bronchitis and other inflammatory disorders. The present study aimed to isolate serratia species producing protease enzyme and increase the enzyme production by optimization of some nutrition demands and environmental conditions, studying the physicochemical properties of the purified protease and in-vivo evaluation of the anti-inflammatory effect of serratiapeptidase by using animal model (rat). Results revealed that out of 170 bacterial isolates retrieved from soil samples collected from different geographical regions, Egypt, only 20 (11.8%) isolates were primarily identified as Serratia species. Serratia S6 was the most potent Serratia isolate in protease production, which preliminary identified by both cultural and morpho-chemical characteristics and finally confirmed by sequencing of 16SrRNA gene and phylogenetic tree | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aEnvironmental conditions | |
| 653 | 4 | _aSerratia | |
| 653 | 4 | _aSerratiapeptidase | |
| 700 | 0 |
_aMagdy Ali Amin , _eSupervisor |
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| 700 | 0 |
_aReham Samir, _eSupervisor |
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| 700 | 0 |
_aWael Mohamed Abuelwafa , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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_aShimaa _eCataloger |
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_2ddc _cTH |
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