| 000 | 02455cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032550.0 | ||
| 008 | 200831s2020 ua d f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.12.10.Ph.D.2020.Am.S | ||
| 100 | 0 | _aAmna Mohamed Abdella | |
| 245 | 1 | 0 |
_aSynthesis and characterization of some novel bis-heterocyclic derivatives / _cAmna Mohamed Abdella ; Supervised Ahmed Helmy Mahmoud Elwahy , Ismail Abdelshafy Abdelhamid , Amr Mohamed Abdelmoniem |
| 246 | 1 | 5 | _aتشييد و توصيف بعض المشتقات الحلقية غير المتجانسة الثنائية والمتماثلة الجديدة |
| 260 |
_aCairo : _bAmna Mohamed Abdella , _c2020 |
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| 300 |
_a151 P. : _bcharts ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Organic Chemistry | ||
| 520 | _aPart 1: Novel bis(1,4-dihydropyridine-3,5-dicarbonitrile) derivatives linked to arene core via ethter amide or ester-amide linkages were prepared by the reaction of the bis-aldehydes with four equivalents of 3-aminocrotononitrile in the presence of acid catalyst. The molecular docking simulation studies indicated that, the prepared compounds bind to the active site of cellular inhibitor apoptotic protein (cIAP1-BIR3).Part 2: One-pot three-component reaction of bis(aldehydes) with 6-aminouracil in boiling acetic acid afforded tetrakis(6-aminopyrimidine-2,4-diones) or bis(tetraoxodecahydropyrido [2,3-d:6,5-d']dipyrimidines) depending on the reaction conditions.Part 3: A synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile), bis(4Hchromene- 3-carbonitrile) and bis(dihydropyrano[3,2-c]chromene) via multicomponent reactions of the appropriate bis-aldehyde with two equivalents of both of malononitrile and 3- methylpyrazol-5-one, dimedone or 4-hydroxycoumarin in a basic solution | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aBis(1,4-dihydropyridine-3,5- dicarbonitrile) | |
| 653 | 4 | _aBis(aldehydes) linked to amide linkages | |
| 653 | 4 | _aTetrakis(6-aminouracil-5-yl)methanes | |
| 700 | 0 |
_aAhmed Helmy Mahmoud Elwahy , _eSupervisor |
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| 700 | 0 |
_aAmr Mohamed Abdelmoniem , _eSupervisor |
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| 700 | 0 |
_aIsmail Abdelshafy Abdelhamid , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c77469 _d77469 |
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