000 02943cam a2200337 a 4500
003 EG-GiCUC
005 20250223032617.0
008 201020s2020 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.10.M.Sc.2020.Ju.M
100 0 _aJulbahar Mahmoud Mohamed Ibrahim
245 1 0 _aMicroneedling for acquired hypomelanosis :
_bA randomized controlled trial /
_cJulbahar Mahmoud Mohamed Ibrahim ; Supervised Khaled Hassan Elhoshy , Vanessa Galal Aly Hafez
246 1 5 _aالوخز بالابرار المجهرى فى علاج نقص الميلانين المكتسب تجربه عشوائية اكلينكية ذات شاهد
260 _aCairo :
_bJulbahar Mahmoud Mohamed Ibrahim ,
_c2020
300 _a111 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology
520 _aBackground:Acquired hypomelanosis is a disease of the skin pigmentation with multiple etiology. Various therapeutic modalities have been described with moderate efficacy.Microneedling is a minimally invasive procedure that stimulates melanogenesis. In comparison to other procedural interventions, microneedling has a short downtime and low risk of infection and scarring due to limited wounding of the epidermis. objective: To determine the efficacy and safety of microneedling in acquired hypomelanosis. methods: Twenty patients,older than 18 years, withacquired hypomelanosis were randomizedinto one of twoarms: ArmA (20 lesions): a single session of microneedling using dermaroller (1.5mm) was performed. Arm B (20 lesions): no-treatment.Peripheral tanning (as demonstrated by mapping), patient{u2019}s satisfaction, surface tanning grade of improvement, VESTA, patient{u2019}s global assessment of improvement and physician{u2019}s global assessment of improvement were used for clinical evaluation after 3 months. results:Both groups showedstatistically clinical improvement after treatment. Side effects and complications were mild and tolerable. conclusion:Medium-depth microneedling deserves to be placed among the armamentarium of therapeutic tools used in the treatment of localized acquired hypomelanosis,both in normal and scarred skin, owing to both its efficacy and safety. Repetitive sessions at 1 to 2 months intervals are suggested to offer better coverage. Interestingly, a possible systemic effect of microneedling was noticed and needs further investigation
530 _aIssued also as CD
653 4 _aAcquired hypomelanosis
653 4 _aHypopigmentation
653 4 _aSkin hypopigmentation
700 0 _aKhaled Hassan Elhoshy ,
_eSupervisor
700 0 _aVanessa Galal Aly Hafez ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c78361
_d78361