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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.12.21.M.Sc.2020.Sh.P
100 0 _aShaimaa Zakaria Eid Khalifa
245 1 0 _aPhysiological impacts of echinochrome pigment on hyperlipidemia induced multiple organs injury in rats /
_cShaimaa Zakaria Eid Khalifa ; Supervised Sohair Ramadan Fahmy , Nashwah Ismail Zaki
246 1 5 _aالتأثيرات الفسيولوجية لصبغ الايكينوكروم على اصابة العديد من الأعضاء المستحث بارتفاع مستوى الدهون فى دم الجرذان
260 _aCairo :
_bShaimaa Zakaria Eid Khalifa ,
_c2020
300 _a142 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology
520 _aObesity has been identified with an expanded danger of a progression of illnesses that include different organ-frameworks of the body. In the present examination, we evaluated the hypolipidemic properties of Echinochrome (Ech) pigment in a high-fat diet (HFD) induced hyperlipidemia in rats. After the hyperlipidemic model was set up, rats were haphazardly separated into four groups as follows: HFD group, Atorvastatin (Ator) group (80 mg/kg), Ech group (1 mg/ kg) and combined group Ator + Ech. In the current study, we investigated the hypolipidemic properties of Ech through testing lipid profile includes serum levels of total lipids (TL), triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), liver functions (AST & ALT), kidney functions (creatinine, urea, and uric acid) and muscle dysfunction marker (creatine kinase; CK) as well as antioxidant markers (MDA, GSH, GST, CAT) in liver, kidney and muscle tissues besides, histo-pathologically studies. The outcomes demonstrated that Ech improved lipid profile, liver functions, kidney functions, and antioxidant markers of HFD rats. The current biochemical results have been confirmed by the histopathological findings. The present investigation indicated that the Ech possesses hypolipidemic potential in hyperlipidemic rat
530 _aIssued also as CD
653 4 _aAtorvastatin
653 4 _aEchinochrome
653 4 _aHigh-fat diet
700 0 _aNashwah Ismail Zaki ,
_eSupervisor
700 0 _aSohair Ramadan Fahmy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c79087
_d79087