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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.24.Ph.D.2020.Mo.F
100 0 _aMostafa Mahmoud Abousebei
245 1 0 _aFunctional improvement of diabetic macular edema after treatment with ranibizumab /
_cMostafa Mahmoud Abousebei ; Supervised Zeinab Saadeldin Elsanabary , Amira Mohamed Elgohary , Moataz Hamed Mohamad
246 1 5 _aالتحسن الوظيفى لارتشاح الشبكيه السكرى بعد العلاج بعقار رانيبيزوماب
260 _aCairo :
_bMostafa Mahmoud Abousebei ,
_c2020
300 _a100 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Ophthalmology
520 _aAim: The aim is to study the role of multifocal Electroretinogram (mfERG) and central visual field test in the evaluation of macular function in patients with diabetic clinically significant macular edema (CSME) and correlate their measurements with central foveal thickness (CFT) as measured by Spectral domain optical coherence tomography (SD-OCT) to elucidate the possible value of mfERG and central visual field in management of diabetic maculopathy.Methods:Thirty eyes were included in this Prospective Cohort interventional study. These thirty eyes belonged to diabetic patients with diabetic macular edema (DME). All subjects were subjected to complete ophthalmic examination, including a review of medical and family history, visual acuity testing by Snellen fraction, and slit-lamp biomicroscopy of anterior and posterior segment. Retinal imaging usingFFA and SD-OCT was done to all patients to obtain the CFT, confirm the clinical diagnosis and detect exclusion criteria e.g. ischemic maculopathy. Afterwards, all included eyes were examined using the mfERG using standard protocols to determine the P1 wave amplitude and implicit time from the foveal region, in addition to central VF to detect the presence of central scotoma and its threshold.Results: P1 amplitude didn{u2019}t show correlation with improvement of the BCVA and CFT, P1 implicit time showed significant improvment in ring 2 of the mfERG after treatment with ranibizumab. MD and PSD showed significant improvement after treatment with ranibizumab
530 _aIssued also as CD
653 4 _aDiabetic macular edema
653 4 _aDiabetic maculopathy
653 4 _aSpectral Domain Optical Coherence Tomography (SD-OCT)
700 0 _aAmira Mohamed Elgohary ,
_eSupervisor
700 0 _aMoataz Hamed Mohamad ,
_eSupervisor
700 0 _aZeinab Saadeldin Elsanabary ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
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_d79425