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003 EG-GiCUC
005 20250223032659.0
008 210125s2020 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.24.03.Ph.D.2020.Ma.P
100 0 _aMarwa Atef Abdelkader Khalifa
245 1 0 _aPulsed dye laser alone versus its combination with topical Ivermectin 1% in treatment of rosacea :
_bRandomized comparative study /
_cMarwa Atef Abdelkader Khalifa ; Supervised Hisham Ali Shokeir , Arwa Mohammad Hassan , Mai Abdelraouf Osman
246 1 5 _aدراسة مقارنة عشوائية بين ليزر الصبغة النبضى و ليزر الصبغة النبضى مع اضافة الايفرميكتين الموضعى 1% فى علاج الوردية
260 _aCairo :
_bMarwa Atef Abdelkader Khalifa ,
_c2020
300 _a167 P . :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - National Institute of Laser - Department of Laser Application in Medical and Biological
520 _aBackground: Rosacea is a chronic disorder characterized by a variety of clinical manifestations. Four subtypes exist. Rosacea is commonly observed in individuals with Fitzpatrick skin types 1 and 2; Females over the age of 30 are most commonly affected. Ivermectin 1% cream is a topical anti-parasitic agent which has a therapeutic effect due to its activity against demodex mites. PDL have become a mainstay for treating PWS, facial telangiectasias, and rosacea due to their safety and efficacy. Aim of the study: the aim of this study was to provide a comprehensive clinical and dermatoscopic comparative study between the efficacy and safety of pulsed dye laser alone versus its combination with topical ivermectin 1% in the treatment of rosacea.Patients and methods: According to treatment protocol the patients were scheduled to undergo 4 laser sessions with 4 week intervals. Regarding PDL treatment, the laser parameters applied in this study were (5to7 mm spot size, a duration of 450 microsecond and a wavelength of 585 nm, 5 to 6.5 j/cm2). Results: The present study demonstrated the clinical and dermatoscopic effectiveness of both PDL and combined PDL and ivermectin 1% cream for the treatment of rosacea. Both groups showed high score of improvement. Moreover the combined PDL and ivermectin 1% cream was found to have a greater treatment effect than PDL alone, according to the improvement score, and satisfaction score. However, this difference wasn't significant (p= 0.296), (p=0.341) in papular and erythema type respectively
530 _aIssued also as CD
653 4 _aPDL
653 4 _aRosacea
653 4 _aTopical Ivermectin 1%
700 0 _aArwa Mohammad Hassan ,
_eSupervisor
700 0 _aHisham Ali Shokeir ,
_eSupervisor
700 0 _aMai Abdelraouf Osman ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAmira
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c79716
_d79716