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003			EG-GiCUC
005			20250223032715.0
008			210314s2021 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.08.03.M.Sc.2021.Ol.A
100	0		_aOla Gamal Hussein
245	1	0	_aAnalytical study of some pharmaceutical compounds containing heterocyclic rings / _cOla Gamal Hussein ; Supervised Mohamed Abdelkawy , Hala Elsayed Zaazaa , Eman Saad Elzanfaly
246	1	5	_aدراسة تحليليه لبعض المركبات الصيدلية المحتوية على الحلقات الغير المتجانسة
260			_aCairo : _bOla Gamal Hussein , _c2021
300			_a224 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520			_aMulticomponent formulations have gained a lot of importance nowadays due to greater patient acceptability, increase potency, multiple action, and quick relief. Simultaneous determination of drugs in combination is an important part in the field of pharmacy as it avoids time of extraction, separation and gets accurate and precise results. Analysis of impurities is very important in the pharmaceutical industry.The possibility of side and toxic effects, and reduced activity of the active substances must be reduced to a minimum. For this reason, different analytical methods were developed to determine Phenazopyridine and Trimethoprim in the presence of Phenazopyridine impurity (2,6-DAP). Most pharmaceutical compounds are subjected to degradation with the subsequent partial or even complete loss of pharmacological activity or the conversion to harmful or toxic substances. A stability indicating procedure may be defined as a procedure that affords selective determination of drug in presence of its degradation products. Thus the development of stability indicating assay has increased enormously. In this thesis, different analytical techniques, namely, spectrophotometry, chemometry, chromatography and voltammetry were developed to determine binary mixture of Phenazopyridine and Trimethoprim in the presence of Phenazopyridine impurity (2,6-DAP).Stability indicating second derivative (2D) spectrophotometry, TLC- densitometry, and voltammetry, were developed to determine Alcaftadine
530			_aIssued also as CD
653		4	_aActive Pharmaceutical Ingredients (APIs)
653		4	_aHeterocyclic rings
653		4	_aPharmaceutical compounds
700	0		_aEman Saad Elzanfaly , _eSupervisor
700	0		_aHala Elsayed Zaazaa , _eSupervisor
700	0		_aMohamed Abdelkawy , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c80224 _d80224