| 000 | 02549cam a2200349 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 005 | 20250223032722.0 | ||
| 008 | 210331s2020 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.12.02.M.Sc.2020.Mo.A | ||
| 100 | 0 | _aMohamed Taher Mahmoud Ali | |
| 245 | 1 | 0 |
_aAssessment of some angiogenic markers in hepatitis C infected patients after therapy / _cMohamed Taher Mahmoud Ali ; Supervised Ahmed Ibrahim Amin , Elshahat Abomosalam Toson , Abdou Osman Abdelhamid |
| 246 | 1 | 5 | _aتقييم بعض دلالات تكوين اوعية دموية جديدة في مرضى الالتهاب الكبدى الوبائى سى بعد العلاج |
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_aCairo : _bMohamed Taher Mahmoud Ali , _c2020 |
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_a149 P . : _bcharts , facsmilies ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry | ||
| 520 | _aThe assessment of liver fibrosis by non-invasive methods before and after treatment is clinically important where hepatitis C virus (HCV) is common in Egypt. Aim: The efficacy of the combined treatment sofosbuvir and ribavirin on HCV infected patients by evaluate the mean serum levels of some direct markers such as Laminin (LN) as fibrogenic marker and platelets derived growth factor (PDGF) and Angiopoietin-1 (Ang-1) as angiogenic markers before and after treatment for the same patients and indirect markers were also included. Also, trying to assess the ability of Ang-1 as a direct marker to differentiate between significant and non-significant fibrosis and the results were compared with those of indirect published score AST/ALT ratio (AAR).This study implying significantly decreased in the mean serum levels of laminin, platelet derived growth factor and angiopoietin-1after treatment. Thus, can be used to assess treatment response and improved liver condition. Also, we found that Ang-1 can help in assessing hepatic fibrosis and superior to AAR score in discriminating the stages of the liver disorders in CHC Egyptian patients | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aAngiopoietin- 1 | |
| 653 | 4 | _aDiagnostic performance | |
| 653 | 4 | _aLiver fibrosis | |
| 700 | 0 |
_aAbdou Osman Abdelhamid , _eSupervisor |
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| 700 | 0 |
_aAhmed Ibrahim Amin , _eSupervisor |
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| 700 | 0 |
_aElshahat Abomosalam Toson , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aAmira _eCataloger |
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| 905 |
_aNazla _eRevisor |
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| 942 |
_2ddc _cTH |
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_c80460 _d80460 |
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