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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.03.M.Sc.2021.He.A
100 0 _aHeidi Ramadan Abdelhadi
245 1 0 _aAnalysis of some drugs containing hydroxyl group /
_cHeidi Ramadan Abdelhadi ; Supervised Hala Elsayd Zaazaa , Maya Shaaban Eissa , Basma Mohamed Eltanany
246 1 5 _aتحليل بعض الادوية التى تحتوى على مجموعة الهيدروكسيل
260 _aCairo :
_bHeidi Ramadan Abdelhadi ,
_c2021
300 _a181 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520 _aThis work is concerned on the quantitative determination of different drugs containing hydroxyl group, namely, Pyridoxine Hydrochloride, (PYR), Doxylamine Succinate (DOX), Chloramphenicol (CHL), Dexmethasone Sodium Phosphate (DSP) and Tetrahydrozoline Hydrochloride (THZ) in their pure form, laboratory prepared mixtures and their pharmaceutical dosage forms. In this study, different analytical techniques were developed, which include spectrophotometric, chemmometric, green chromatographic and voltammetric methods for estimation of the drugs under study and different applications were developed e.g dissolution test and bioanalytical applications. Several experimental conditions were developed for optimization of the adopted methods. Since degradation of pharmaceutical compounds may result in partial or complete loss of the pharmacological activity with propability of producing toxic or harmful substance, stability indicating assay methods were developed for the determination of the intact drug in presence of their degradation products
530 _aIssued also as CD
653 4 _aChloramphenicol (CHL)
653 4 _aPyridoxine Hydrochloride (PYR)
653 4 _aTetrahydrozoline Hydrochloride (THZ)
700 0 _aBasma Mohamed Eltanany ,
_eSupervisor
700 0 _aHala Elsayd Zaazaa ,
_eSupervisor
700 0 _aMaya Shaaban Eissa ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c81758
_d81758