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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.18.M.Sc.2021.Ta.S
100 0 _aTasneem Khaled Mostafa Mahmoud
245 1 0 _aStudy of the brachial artery distensibility in hypothyroidism in correlation with serum calcium and phosphorus /
_cTasneem Khaled Mostafa Mahmoud ; Supervised Afaf Abdeltawab Hemeda , Ahmed Mohammed Abdelhamid Soliman , Ghada Rabea Abdelaziz Ahmed
246 1 5 _aدراسة قابلية تمدد الشريان العضدى فى مرض قصور الغدة الدرقية وعلاقته بنسبة الكالسيوم والفسفور فى السيروم
260 _aCairo :
_bTasneem Khaled Mostafa Mahmoud ,
_c2021
300 _a90 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
520 _aBackground: Thyroid hormone has both genomic and non- genomic effect on blood vessels. It reduces systemic vascular resistance by multiple mechanisms.Hypothyroidism shares several mechanisms involved in the process of arterial wall stiffness. Among studies of hypothyroid patients, there is increased serum phosphorus levels. Calcification of vascular system is characterised by deposition of calcium phosphate, which can result in increased stiffness. Aims: to study brachial artery distensibility in hypothyroid patients and to correlate with serum calcium and phosphorus levels. Methods:The study included 33newly diagnosed hypothyroid patients and 33 age-matched healthy subjects.Subjects in both groups were examined for brachial artery distensibility. The groups will be compared with each other regarding the vascular study results that will be correlated with laboratory data in the studied patients. Results:There is a significant positive correlation of brachial artery diameter in all stages with both of TSH level and age.There is no statistically significance regarding brachial distensibility and serum calcium and phosphorus. Conclusions: Brachial artery distensibility is affected in hypothyroid patientswhichindicates positive correlation between arterial stiffness and hypothyroidism
530 _aIssued also as CD
653 4 _aBrachial artery
653 4 _aDistensibility
653 4 _aHypothyroidism
700 0 _aAfaf Abdeltawab Hemeda ,
_eSupervisor
700 0 _aAhmed Mohammed Abdelhamid Soliman ,
_eSupervisor
700 0 _aGhada Rabea Abdelaziz Ahmed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c82500
_d82500