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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2021.Sa.A
100 0 _aSameh Gamal Ebrahim Sakr
245 1 0 _aAssociation between vitamin D levels and early onset sepsis in newborns /
_cSameh Gamal Ebrahim Sakr ; Supervised Dalia Sayed Mosallam , Christine William Shaker Basanti , Dena Hesham Ahmed
246 1 5 _aالعلاقة بين مستوي فيتامين د و حدوث تسمم فى الدم عند حديثى الولادة
260 _aCairo :
_bSameh Gamal Ebrahim Sakr ,
_c2021
300 _a97 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aItamin D, the sunshine vitamin, has received a lot of attention recently as a result of a meteoric rise in the number of publications showing that vitamin D plays a crucial role in a plethora of physiological functions and associating vitamin D deficiency with many acute and chronic illnesses including disorders of calcium metabolism, autoimmune diseases, some cancers, type 2 diabetes mellitus, cardiovascular disease and infectious diseases. Vitamin D deficiency is now recognized as a global pandemic (Wacker and Holick, 2013).Neonatal sepsis is a clinical syndrome characterized by signs and symptoms of infection with or without accompanyingbacterimia in the first month of life. Early-onset sepsis (EOS) occurs within 3 days of life as defined by the National Institute of Child Health and Human Development and Vermont Oxford Networks (Sahay and Sahay, 2015). Vitamin D has an important role in the regulation of both the innate and acquired immune systems.Newborns are more susceptible to infections as both innate and acquired immune systems are not entirely developed. Therefore, low vitamin D status is expected to be one of the risk factors for early onset neonatal sepsis (Aly and Abdel Hady, 2015). Kumar et al. (2019) determined the possible association between neonatal vitamin D levels and EOS in term neonates. They reported that lower neonatal 25-OHD levels are associated with EOS. Adequate vitamin D supplementation during pregnancy may be helpful to prevent EOS in term neonates
530 _aIssued also as CD
653 4 _aEarly onset sepsis
653 4 _aNewborns
653 4 _aVitamin D levels
700 0 _aChristine William Shaker Basanti ,
_eSupervisor
700 0 _aDalia Sayed Mosallam ,
_eSupervisor
700 0 _aDena Hesham Ahmed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c83593
_d83593