000			03098cam a2200349 a 4500
003			EG-GiCUC
005			20250223032902.0
008			211221s2020 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.24.03.Ph.D.2020.Na.C
100	0		_aNahla Abdelaziz Mohamed Ibrahim
245	1	0	_aComparative randomized study between the effect of photodynamic therapy and intralesional "vitamin D3" injection for the treatment of recalcitrant palmoplanter warts / _cNahla Abdelaziz Mohamed Ibrahim ; Supervised Abeer Attia Tawfik , Maha Fadel Mohamed , Doaa Ahmed Abdel Fadeel
246	1	5	_aدراسة مقارنة عشوائية بين تأثير المعالجة الضوئية الديناميكية و العلاج عن طريق حقن (فيتامين د) داخل الآفة لعلاج الثأليل الأخمصية والكفية المستعصية
260			_aCairo : _bNahla Abdelaziz Mohamed Ibrahim , _c2020
300			_a141 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Application in Medical Biololgical
520			_aBackground: Recalcitrant palmoplantar warts represent a therapeutic challenge. Side effects of local destructive methods necessitate the need for other less morbid modalities. Recently immunotherapy as well as light based devices and lasers have emerged as therapeutic approaches. Aim of the study: To compare between the safety and efficacy of intralesional vitamin D3 injection and photodynamic therapy (PDT) using eosin in treatment of recalcitrant palmoplantar warts. Patients and Methods: Prospective, randomized, controlled comparative study. Fifty six patients with recalcitrant palmoplantar warts were randomly divided into 3 groups. Group A was injected with intralesional vitamin D3. Group B was subjected to PDT using eosin loaded in transfersomes as a photosensitizer. Group C is the control group. Clinical improvement was assessed by photographic records and dermoscopic assessment, at baseline, before each session and after completion of treatment. Patients were followed up for 6 months after cure to detect recurrence.Results: Group A and B showed complete clearance in 88.89 % and 86.36 % respectively compared to 18.75 % in the control group. These results were statistically significant (P value<0.001). No side effects were reported except for pain during injection in group A. Conclusion: In the current study, both vitamin D3 and PDT using Eosin are safe, highly effective and well tolerated modalities in treatment of viral warts
530			_aIssued also as CD
653		4	_aPhotodynamic therapy
653		4	_aVitamin D3
653		4	_aWarts
700	0		_aAbeer Attia Tawfik , _eSupervisor
700	0		_aDoaa Ahmed Abdelfadeel , _eSupervisor
700	0		_aMaha Fadel Mohamed , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c83648 _d83648