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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.03.M.Sc.2021.Ra.A
100 0 _aRana Elsayed Yusef Sherif
245 1 0 _aAnalysis of some UV filters used in skin care and cosmetic products /
_cRana Elsayed Yusef Sherif ; Supervised Sawsan Mohammed Amer , Ghada Abdelhamid Sedik , Hanan Mohamed Elwy
246 1 5 _aتحليل لبعض مرشحات الاشعة فوق البنفسجية المستخدمة فى مستحضرات العناية بالبشرة ومستحضرات التجميل
260 _aCairo :
_bRana Elsayed Yusef Sherif ,
_c2021
300 _a226 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520 _aUV filters recently gained a lot of interest as they are intended to protect human skin against UV radiation, and for this reason they are increasingly added to many personal care products. This thesis deals with the study of different UV filters namely Benzophenone-4 (BZ4) and Benzophenone-3 (BZ3) in combination with Octyl methoxycinnamate (OMC) as a coformulated drug. Different analytical techniques including chromatographic, spectroscopic and electrochemical ones were adopted for the determination of the studied drugs either in their pure form or their pharmaceutical formulations. Different experimental conditions were studied till reaching the optimum conditions.The chromatographic methods utilize the power of HPLC and TLC densitometry for quantification of the studied drugs in their pure form and in presence of their stress induced degradation products.While different spectroscopic methods were introduced for BZ4 determination with acceptable results. Finally two electrochemical methods were developed and validated implying novel modified MWCNTs sensor in addition to molecularly imprinted polymer modified Carbon paste sensor for highly sensitive determination of BZ4. All suggested methods were validated according to ICH guide lines and compared statistically to reported methods where no significant difference regarding accuracy and precision was observed
530 _aIssued also as CD
653 4 _aChromatography
653 4 _aSpectroscopy
653 4 _aUV filters
700 0 _aGhada Abdelhamid Sedik ,
_eSupervisor
700 0 _aHanan Mohamed Elwy ,
_eSupervisor
700 0 _aSawsan Mohammed Amer ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c83709
_d83709