Single nucleotide polymorphism (SNP) rs8099917 as a predictive factor of virological response to pegylated interferon plus ribavirin in treatment of chronic hepatitis C virus patients /
Ahmed Mohamed Eldeeb
Single nucleotide polymorphism (SNP) rs8099917 as a predictive factor of virological response to pegylated interferon plus ribavirin in treatment of chronic hepatitis C virus patients / استخدام النيكوليوتيد الفردى متعدد الأشكال (رس8099917) كوسيلة تنبؤية للاستجابة للانترفيرون طويل المفعول و الريبافيرين فى علاج مرضى فيروس سى الكبدى المزمن Ahmed Mohamed Eldeeb ; Supervised Gamal Eldin Esmat , Wahid Halim Doss , Mohamed Ali Saber - Cairo : Ahmed Mohamed Eldeeb , 2014 - 155 P. : charts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine
Introduction: For SNP rs8099917, the favorable T allele is associated with a higher SVR after PEG - IFN alpha/RBV therapy while the G allele is a risk factor for non - response. Aim of work: Is to assess the value of (SNP) rs8099917 as a predictor of SVR. Methods: This study is a retrospective controlled study and was performed on a total number of 240 patients who were treated by PEG - IFN alpha/RBV for 48 weeks and (SNP) rs8099917 was done for the all patients. Results: TT genotype was more prevalent in SVR group than TG and GG genotypes. Conclusion: Determination of (SNP) rs8099917 before starting antiviral therapy may thus serve as a good response predictor
HCV Interleukin 28b SNP rs8099917 Pegylated interferon
Single nucleotide polymorphism (SNP) rs8099917 as a predictive factor of virological response to pegylated interferon plus ribavirin in treatment of chronic hepatitis C virus patients / استخدام النيكوليوتيد الفردى متعدد الأشكال (رس8099917) كوسيلة تنبؤية للاستجابة للانترفيرون طويل المفعول و الريبافيرين فى علاج مرضى فيروس سى الكبدى المزمن Ahmed Mohamed Eldeeb ; Supervised Gamal Eldin Esmat , Wahid Halim Doss , Mohamed Ali Saber - Cairo : Ahmed Mohamed Eldeeb , 2014 - 155 P. : charts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine
Introduction: For SNP rs8099917, the favorable T allele is associated with a higher SVR after PEG - IFN alpha/RBV therapy while the G allele is a risk factor for non - response. Aim of work: Is to assess the value of (SNP) rs8099917 as a predictor of SVR. Methods: This study is a retrospective controlled study and was performed on a total number of 240 patients who were treated by PEG - IFN alpha/RBV for 48 weeks and (SNP) rs8099917 was done for the all patients. Results: TT genotype was more prevalent in SVR group than TG and GG genotypes. Conclusion: Determination of (SNP) rs8099917 before starting antiviral therapy may thus serve as a good response predictor
HCV Interleukin 28b SNP rs8099917 Pegylated interferon