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Enhancement of the therapeutic efficacy of anticancer drug using magnetic gold nanocarriers /

Mohammed Mahmoud Fathy Ahmed

Enhancement of the therapeutic efficacy of anticancer drug using magnetic gold nanocarriers / تحسين الكفاءة العلاجية للعقار المضاد للأورام بإستخدام جزيئات الذهب المغناطيسية النانومترية كحاملات للعقاقير Mohammed Mahmoud Fathy Ahmed ; Supervised Wafaa A. Khlial , Nihal S. Elbialy - Cairo : Mohammed Mahmoud Fathy Ahmed , 2014 - 110 P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics

Treatment of approximately 50% of human cancers includes the use of chemotherapy. The major problem associated with chemotherapy is the inability to deliver pharmaceuticals to specific site of the body without inducing normal tissue toxicity. Consequently, the efficiency of chemotherapy could potentially be improved by the development of a targeted drug nanocarriers that would enhance the effective water solubility of hydrophobic anticancer drugs as well as the selective delivery of drugs to malignant tissues. Thereby increasing the curative effectiveness of the cancer treatment while sparing normal tissues from the side effects of the chemotherapeutic agent



Doxorubicin Magnetic targeted drug delivery (MTD Nanoparticles