Retinoid Receptor Expression and Its Correlation to Retinoid Sensitivity in Non - M3 Acute Myeloid Leukemia Blast Cells /
Samah Mohamed Abdelhamid
Retinoid Receptor Expression and Its Correlation to Retinoid Sensitivity in Non - M3 Acute Myeloid Leukemia Blast Cells / التعبير عن مستقبل الريتينويد ودراسة مقدار حساسيته لمادة الريتينويد فى حالات سرطان الدم الميلويدى الحاد ما عدا ام3 Samah Mohamed Abd El Hamid ; Supervised Naila Abdelfattah Omran , Mervat Mohamed ElAnsary , Mervat Mohamed Wageh Mattar - Cairo : Samah Mohamed Abdelhamid , 2006 - 214p : ill ; 25cm
Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology
RAR - receptor is expressed and up - regulated in response to ATRA in a good proportion of patients with AMLA considerable variability was noticed regarding the basal expression levels and the amplitude of up - regulationFAB subtypes and CD34 expression may influence the response to ATRA but other contributing factors should be consideredUp - regulation of RAR - ? receptor expression in AML was not associated with granulocytic maturationSince the retinoid protocols for non - M3 AML patients have drawn attention in the past years , the ability to express and up - regulate RAR - receptor in AML leukemic cells may be useful as predictive test during treatment with retinoids especially with the availability of real time PCR as a sensitive , specific , rapid and quantitative assay for RAR - receptor expressio
non M3 AML Real - time PCR Retinoid Receptor
Retinoid Receptor Expression and Its Correlation to Retinoid Sensitivity in Non - M3 Acute Myeloid Leukemia Blast Cells / التعبير عن مستقبل الريتينويد ودراسة مقدار حساسيته لمادة الريتينويد فى حالات سرطان الدم الميلويدى الحاد ما عدا ام3 Samah Mohamed Abd El Hamid ; Supervised Naila Abdelfattah Omran , Mervat Mohamed ElAnsary , Mervat Mohamed Wageh Mattar - Cairo : Samah Mohamed Abdelhamid , 2006 - 214p : ill ; 25cm
Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology
RAR - receptor is expressed and up - regulated in response to ATRA in a good proportion of patients with AMLA considerable variability was noticed regarding the basal expression levels and the amplitude of up - regulationFAB subtypes and CD34 expression may influence the response to ATRA but other contributing factors should be consideredUp - regulation of RAR - ? receptor expression in AML was not associated with granulocytic maturationSince the retinoid protocols for non - M3 AML patients have drawn attention in the past years , the ability to express and up - regulate RAR - receptor in AML leukemic cells may be useful as predictive test during treatment with retinoids especially with the availability of real time PCR as a sensitive , specific , rapid and quantitative assay for RAR - receptor expressio
non M3 AML Real - time PCR Retinoid Receptor